Angptl8 mediates food-driven resetting of hepatic circadian clock in mice
The circadian clock regulates rhythms of behavior and physiology and the timing of circadian rhythms in liver is influenced by food intake. Here, the authors identify the hepatokine Angptl8 as a mediator of liver clock food entrainment.
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Nature Portfolio
2019
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oai:doaj.org-article:033c8e19e26e422587263c408fb3aec12021-12-02T14:40:19ZAngptl8 mediates food-driven resetting of hepatic circadian clock in mice10.1038/s41467-019-11513-12041-1723https://doaj.org/article/033c8e19e26e422587263c408fb3aec12019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11513-1https://doaj.org/toc/2041-1723The circadian clock regulates rhythms of behavior and physiology and the timing of circadian rhythms in liver is influenced by food intake. Here, the authors identify the hepatokine Angptl8 as a mediator of liver clock food entrainment.Siyu ChenMengyang FengShiyao ZhangZhewen DongYifan WangWenxiang ZhangChang LiuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019) |
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Science Q Siyu Chen Mengyang Feng Shiyao Zhang Zhewen Dong Yifan Wang Wenxiang Zhang Chang Liu Angptl8 mediates food-driven resetting of hepatic circadian clock in mice |
description |
The circadian clock regulates rhythms of behavior and physiology and the timing of circadian rhythms in liver is influenced by food intake. Here, the authors identify the hepatokine Angptl8 as a mediator of liver clock food entrainment. |
format |
article |
author |
Siyu Chen Mengyang Feng Shiyao Zhang Zhewen Dong Yifan Wang Wenxiang Zhang Chang Liu |
author_facet |
Siyu Chen Mengyang Feng Shiyao Zhang Zhewen Dong Yifan Wang Wenxiang Zhang Chang Liu |
author_sort |
Siyu Chen |
title |
Angptl8 mediates food-driven resetting of hepatic circadian clock in mice |
title_short |
Angptl8 mediates food-driven resetting of hepatic circadian clock in mice |
title_full |
Angptl8 mediates food-driven resetting of hepatic circadian clock in mice |
title_fullStr |
Angptl8 mediates food-driven resetting of hepatic circadian clock in mice |
title_full_unstemmed |
Angptl8 mediates food-driven resetting of hepatic circadian clock in mice |
title_sort |
angptl8 mediates food-driven resetting of hepatic circadian clock in mice |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/033c8e19e26e422587263c408fb3aec1 |
work_keys_str_mv |
AT siyuchen angptl8mediatesfooddrivenresettingofhepaticcircadianclockinmice AT mengyangfeng angptl8mediatesfooddrivenresettingofhepaticcircadianclockinmice AT shiyaozhang angptl8mediatesfooddrivenresettingofhepaticcircadianclockinmice AT zhewendong angptl8mediatesfooddrivenresettingofhepaticcircadianclockinmice AT yifanwang angptl8mediatesfooddrivenresettingofhepaticcircadianclockinmice AT wenxiangzhang angptl8mediatesfooddrivenresettingofhepaticcircadianclockinmice AT changliu angptl8mediatesfooddrivenresettingofhepaticcircadianclockinmice |
_version_ |
1718390335982272512 |