Corneal endothelial cell density and morphology in Phramongkutklao Hospital

Narumon Sopapornamorn1, Manapon Lekskul1, Suthee Panichkul21Department of Ophthalmology, Phramongkutklao Hospital, Bangkok, Thailand; 2Department of Obstetrics and Gynecology, Phramongkutklao College of Medicine, Bangkok, ThailandObjective: To describe the corneal endothelial density and morphology...

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Autores principales: Narumon Sopapornamorn, Manapon Lekskul, Suthee Panichkul
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Lenguaje:EN
Publicado: Dove Medical Press 2008
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spelling oai:doaj.org-article:033d4390807947678db732f4d5b875c12021-12-02T00:56:51ZCorneal endothelial cell density and morphology in Phramongkutklao Hospital1177-54671177-5483https://doaj.org/article/033d4390807947678db732f4d5b875c12008-03-01T00:00:00Zhttp://www.dovepress.com/corneal-endothelial-cell-density-and-morphology-in-phramongkutklao-hos-a342https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Narumon Sopapornamorn1, Manapon Lekskul1, Suthee Panichkul21Department of Ophthalmology, Phramongkutklao Hospital, Bangkok, Thailand; 2Department of Obstetrics and Gynecology, Phramongkutklao College of Medicine, Bangkok, ThailandObjective: To describe the corneal endothelial density and morphology in patients of Phramongkutklao Hospital and the relationship between endothelial cell parameters and other factors.Methods: Four hundred and four eyes of 202 volunteers were included. Noncontact specular microscopy was performed after taking a history and testing the visual acuity, intraocular pressure measurement, Schirmer’s test and routine eye examination by slit lamp microscope. The studied parameters included mean endothelial cell density (MCD), coefficient of variation (CV), and percentage of hexagonality.Results: The mean age of volunteers was 45.73 years; the range being 20 to 80 years old. Their MCD (SD), mean percentage of CV (SD) and mean (SD) percentage of hexagonality were 2623.49(325) cell/mm2, 39.43(8.23)% and 51.50(10.99)%, respectively. Statistically, MCD decreased significantly with age (p < 0.01). There was a significant difference in the percentage of CV between genders. There was no statistical significance between parameters and other factors.Conclusion: The normative data of the corneal endothelium of Thai eyes indicated that, statistically, MCD decreased significantly with age. Previous studies have reported no difference in MCD, percentage of CV, and percentage of hexagonality between gender. Nevertheless, significantly different percentages of CV between genders were presented in this study.Keywords: Corneal endothelial cell, parameters, age, gender, smoking, Thailand Narumon SopapornamornManapon LekskulSuthee PanichkulDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2008, Iss Issue 1, Pp 147-151 (2008)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Narumon Sopapornamorn
Manapon Lekskul
Suthee Panichkul
Corneal endothelial cell density and morphology in Phramongkutklao Hospital
description Narumon Sopapornamorn1, Manapon Lekskul1, Suthee Panichkul21Department of Ophthalmology, Phramongkutklao Hospital, Bangkok, Thailand; 2Department of Obstetrics and Gynecology, Phramongkutklao College of Medicine, Bangkok, ThailandObjective: To describe the corneal endothelial density and morphology in patients of Phramongkutklao Hospital and the relationship between endothelial cell parameters and other factors.Methods: Four hundred and four eyes of 202 volunteers were included. Noncontact specular microscopy was performed after taking a history and testing the visual acuity, intraocular pressure measurement, Schirmer’s test and routine eye examination by slit lamp microscope. The studied parameters included mean endothelial cell density (MCD), coefficient of variation (CV), and percentage of hexagonality.Results: The mean age of volunteers was 45.73 years; the range being 20 to 80 years old. Their MCD (SD), mean percentage of CV (SD) and mean (SD) percentage of hexagonality were 2623.49(325) cell/mm2, 39.43(8.23)% and 51.50(10.99)%, respectively. Statistically, MCD decreased significantly with age (p < 0.01). There was a significant difference in the percentage of CV between genders. There was no statistical significance between parameters and other factors.Conclusion: The normative data of the corneal endothelium of Thai eyes indicated that, statistically, MCD decreased significantly with age. Previous studies have reported no difference in MCD, percentage of CV, and percentage of hexagonality between gender. Nevertheless, significantly different percentages of CV between genders were presented in this study.Keywords: Corneal endothelial cell, parameters, age, gender, smoking, Thailand
format article
author Narumon Sopapornamorn
Manapon Lekskul
Suthee Panichkul
author_facet Narumon Sopapornamorn
Manapon Lekskul
Suthee Panichkul
author_sort Narumon Sopapornamorn
title Corneal endothelial cell density and morphology in Phramongkutklao Hospital
title_short Corneal endothelial cell density and morphology in Phramongkutklao Hospital
title_full Corneal endothelial cell density and morphology in Phramongkutklao Hospital
title_fullStr Corneal endothelial cell density and morphology in Phramongkutklao Hospital
title_full_unstemmed Corneal endothelial cell density and morphology in Phramongkutklao Hospital
title_sort corneal endothelial cell density and morphology in phramongkutklao hospital
publisher Dove Medical Press
publishDate 2008
url https://doaj.org/article/033d4390807947678db732f4d5b875c1
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