Transcriptomic and anatomic parcellation of 5-HT3AR expressing cortical interneuron subtypes revealed by single-cell RNA sequencing

Cortical GABAergic interneurons are highly diverse in their gene expression, electrophysiological properties, and connectivity. Here the authors reveal three distinct subtypes of Htr3a-GFP+ interneurons using the single-cell RNA-seq approach, and identify MEIS2 as a marker for one such subtype.

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Autores principales:	Sarah Frazer, Julien Prados, Mathieu Niquille, Christelle Cadilhac, Foivos Markopoulos, Lucia Gomez, Ugo Tomasello, Ludovic Telley, Anthony Holtmaat, Denis Jabaudon, Alexandre Dayer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0340c5fb5b684f8f9a8aac3024107581
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spelling	oai:doaj.org-article:0340c5fb5b684f8f9a8aac30241075812021-12-02T15:39:06ZTranscriptomic and anatomic parcellation of 5-HT3AR expressing cortical interneuron subtypes revealed by single-cell RNA sequencing10.1038/ncomms142192041-1723https://doaj.org/article/0340c5fb5b684f8f9a8aac30241075812017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms14219https://doaj.org/toc/2041-1723Cortical GABAergic interneurons are highly diverse in their gene expression, electrophysiological properties, and connectivity. Here the authors reveal three distinct subtypes of Htr3a-GFP+ interneurons using the single-cell RNA-seq approach, and identify MEIS2 as a marker for one such subtype.Sarah FrazerJulien PradosMathieu NiquilleChristelle CadilhacFoivos MarkopoulosLucia GomezUgo TomaselloLudovic TelleyAnthony HoltmaatDenis JabaudonAlexandre DayerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sarah Frazer Julien Prados Mathieu Niquille Christelle Cadilhac Foivos Markopoulos Lucia Gomez Ugo Tomasello Ludovic Telley Anthony Holtmaat Denis Jabaudon Alexandre Dayer Transcriptomic and anatomic parcellation of 5-HT3AR expressing cortical interneuron subtypes revealed by single-cell RNA sequencing
description	Cortical GABAergic interneurons are highly diverse in their gene expression, electrophysiological properties, and connectivity. Here the authors reveal three distinct subtypes of Htr3a-GFP+ interneurons using the single-cell RNA-seq approach, and identify MEIS2 as a marker for one such subtype.
format	article
author	Sarah Frazer Julien Prados Mathieu Niquille Christelle Cadilhac Foivos Markopoulos Lucia Gomez Ugo Tomasello Ludovic Telley Anthony Holtmaat Denis Jabaudon Alexandre Dayer
author_facet	Sarah Frazer Julien Prados Mathieu Niquille Christelle Cadilhac Foivos Markopoulos Lucia Gomez Ugo Tomasello Ludovic Telley Anthony Holtmaat Denis Jabaudon Alexandre Dayer
author_sort	Sarah Frazer
title	Transcriptomic and anatomic parcellation of 5-HT3AR expressing cortical interneuron subtypes revealed by single-cell RNA sequencing
title_short	Transcriptomic and anatomic parcellation of 5-HT3AR expressing cortical interneuron subtypes revealed by single-cell RNA sequencing
title_full	Transcriptomic and anatomic parcellation of 5-HT3AR expressing cortical interneuron subtypes revealed by single-cell RNA sequencing
title_fullStr	Transcriptomic and anatomic parcellation of 5-HT3AR expressing cortical interneuron subtypes revealed by single-cell RNA sequencing
title_full_unstemmed	Transcriptomic and anatomic parcellation of 5-HT3AR expressing cortical interneuron subtypes revealed by single-cell RNA sequencing
title_sort	transcriptomic and anatomic parcellation of 5-ht3ar expressing cortical interneuron subtypes revealed by single-cell rna sequencing
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/0340c5fb5b684f8f9a8aac3024107581
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Transcriptomic and anatomic parcellation of 5-HT3AR expressing cortical interneuron subtypes revealed by single-cell RNA sequencing

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