Trapping mammalian protein complexes in viral particles

Trapping mammalian protein complexes in viral particles

A large portion of the proteome carries out its cellular function as part of macromolecular complexes. Here the authors describe Virotrap, a novel lysis-free approach for the isolation and identification of biologically relevant protein-protein and small molecule-protein interactions.

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Autores principales: Sven Eyckerman, Kevin Titeca, Emmy Van Quickelberghe, Eva Cloots, Annick Verhee, Noortje Samyn, Leentje De Ceuninck, Evy Timmerman, Delphine De Sutter, Sam Lievens, Serge Van Calenbergh, Kris Gevaert, Jan Tavernier
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Science
Q
Acceso en línea:https://doaj.org/article/034899752e504bb59ee91df15e16d4af
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spelling oai:doaj.org-article:034899752e504bb59ee91df15e16d4af2021-12-02T17:33:07ZTrapping mammalian protein complexes in viral particles10.1038/ncomms114162041-1723https://doaj.org/article/034899752e504bb59ee91df15e16d4af2016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11416https://doaj.org/toc/2041-1723A large portion of the proteome carries out its cellular function as part of macromolecular complexes. Here the authors describe Virotrap, a novel lysis-free approach for the isolation and identification of biologically relevant protein-protein and small molecule-protein interactions.Sven EyckermanKevin TitecaEmmy Van QuickelbergheEva ClootsAnnick VerheeNoortje SamynLeentje De CeuninckEvy TimmermanDelphine De SutterSam LievensSerge Van CalenberghKris GevaertJan TavernierNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sven Eyckerman
Kevin Titeca
Emmy Van Quickelberghe
Eva Cloots
Annick Verhee
Noortje Samyn
Leentje De Ceuninck
Evy Timmerman
Delphine De Sutter
Sam Lievens
Serge Van Calenbergh
Kris Gevaert
Jan Tavernier
Trapping mammalian protein complexes in viral particles
description A large portion of the proteome carries out its cellular function as part of macromolecular complexes. Here the authors describe Virotrap, a novel lysis-free approach for the isolation and identification of biologically relevant protein-protein and small molecule-protein interactions.
format article
author Sven Eyckerman
Kevin Titeca
Emmy Van Quickelberghe
Eva Cloots
Annick Verhee
Noortje Samyn
Leentje De Ceuninck
Evy Timmerman
Delphine De Sutter
Sam Lievens
Serge Van Calenbergh
Kris Gevaert
Jan Tavernier
author_facet Sven Eyckerman
Kevin Titeca
Emmy Van Quickelberghe
Eva Cloots
Annick Verhee
Noortje Samyn
Leentje De Ceuninck
Evy Timmerman
Delphine De Sutter
Sam Lievens
Serge Van Calenbergh
Kris Gevaert
Jan Tavernier
author_sort Sven Eyckerman
title Trapping mammalian protein complexes in viral particles
title_short Trapping mammalian protein complexes in viral particles
title_full Trapping mammalian protein complexes in viral particles
title_fullStr Trapping mammalian protein complexes in viral particles
title_full_unstemmed Trapping mammalian protein complexes in viral particles
title_sort trapping mammalian protein complexes in viral particles
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/034899752e504bb59ee91df15e16d4af
work_keys_str_mv AT sveneyckerman trappingmammalianproteincomplexesinviralparticles
AT kevintiteca trappingmammalianproteincomplexesinviralparticles
AT emmyvanquickelberghe trappingmammalianproteincomplexesinviralparticles
AT evacloots trappingmammalianproteincomplexesinviralparticles
AT annickverhee trappingmammalianproteincomplexesinviralparticles
AT noortjesamyn trappingmammalianproteincomplexesinviralparticles
AT leentjedeceuninck trappingmammalianproteincomplexesinviralparticles
AT evytimmerman trappingmammalianproteincomplexesinviralparticles
AT delphinedesutter trappingmammalianproteincomplexesinviralparticles
AT samlievens trappingmammalianproteincomplexesinviralparticles
AT sergevancalenbergh trappingmammalianproteincomplexesinviralparticles
AT krisgevaert trappingmammalianproteincomplexesinviralparticles
AT jantavernier trappingmammalianproteincomplexesinviralparticles
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