WNK3 promotes the invasiveness of glioma cell lines under hypoxia by inducing the epithelial-to-mesenchymal transition

The primary features of malignant glioma include high rates of mortality and recurrence, uncontrollable invasiveness, strong angiogenesis, and widespread hypoxia. The hypoxic microenvironment is an important factor affecting the malignant progression of glioma. However, the molecular mechanisms unde...

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Autores principales:	Wang Yue, Wu Bingbing, Long Shengrong, QiangLiu, Li Guangyu
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2021
Materias:	glioma hypoxia wnk3 invasiveness Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Acceso en línea:	https://doaj.org/article/0348ad29efe949cf8da3d9706c97b782
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spelling	oai:doaj.org-article:0348ad29efe949cf8da3d9706c97b7822021-12-05T14:11:05ZWNK3 promotes the invasiveness of glioma cell lines under hypoxia by inducing the epithelial-to-mesenchymal transition2081-693610.1515/tnsci-2020-0180https://doaj.org/article/0348ad29efe949cf8da3d9706c97b7822021-08-01T00:00:00Zhttps://doi.org/10.1515/tnsci-2020-0180https://doaj.org/toc/2081-6936The primary features of malignant glioma include high rates of mortality and recurrence, uncontrollable invasiveness, strong angiogenesis, and widespread hypoxia. The hypoxic microenvironment is an important factor affecting the malignant progression of glioma. However, the molecular mechanisms underlying glioma adaption in hypoxic microenvironments are poorly understood.Wang YueWu BingbingLong ShengrongQiangLiuLi GuangyuDe Gruyterarticlegliomahypoxiawnk3invasivenessNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571ENTranslational Neuroscience, Vol 12, Iss 1, Pp 320-329 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	glioma hypoxia wnk3 invasiveness Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
spellingShingle	glioma hypoxia wnk3 invasiveness Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Wang Yue Wu Bingbing Long Shengrong QiangLiu Li Guangyu WNK3 promotes the invasiveness of glioma cell lines under hypoxia by inducing the epithelial-to-mesenchymal transition
description	The primary features of malignant glioma include high rates of mortality and recurrence, uncontrollable invasiveness, strong angiogenesis, and widespread hypoxia. The hypoxic microenvironment is an important factor affecting the malignant progression of glioma. However, the molecular mechanisms underlying glioma adaption in hypoxic microenvironments are poorly understood.
format	article
author	Wang Yue Wu Bingbing Long Shengrong QiangLiu Li Guangyu
author_facet	Wang Yue Wu Bingbing Long Shengrong QiangLiu Li Guangyu
author_sort	Wang Yue
title	WNK3 promotes the invasiveness of glioma cell lines under hypoxia by inducing the epithelial-to-mesenchymal transition
title_short	WNK3 promotes the invasiveness of glioma cell lines under hypoxia by inducing the epithelial-to-mesenchymal transition
title_full	WNK3 promotes the invasiveness of glioma cell lines under hypoxia by inducing the epithelial-to-mesenchymal transition
title_fullStr	WNK3 promotes the invasiveness of glioma cell lines under hypoxia by inducing the epithelial-to-mesenchymal transition
title_full_unstemmed	WNK3 promotes the invasiveness of glioma cell lines under hypoxia by inducing the epithelial-to-mesenchymal transition
title_sort	wnk3 promotes the invasiveness of glioma cell lines under hypoxia by inducing the epithelial-to-mesenchymal transition
publisher	De Gruyter
publishDate	2021
url	https://doaj.org/article/0348ad29efe949cf8da3d9706c97b782
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WNK3 promotes the invasiveness of glioma cell lines under hypoxia by inducing the epithelial-to-mesenchymal transition

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