Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function
Aging is associated with a progressive loss of muscle function. Here the authors characterize mitochondrial capacity and muscle function in young and older adults with similar habitual physical activity and also compared to older adults with exercise training or with physical impairment.
Saved in:
| Main Authors: | , , , , , , , , , , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2021
|
| Subjects: | |
| Online Access: | https://doaj.org/article/035190f53f0041ab9013b063d3712f34 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| id |
oai:doaj.org-article:035190f53f0041ab9013b063d3712f34 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:035190f53f0041ab9013b063d3712f342021-12-02T18:49:37ZImpact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function10.1038/s41467-021-24956-22041-1723https://doaj.org/article/035190f53f0041ab9013b063d3712f342021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24956-2https://doaj.org/toc/2041-1723Aging is associated with a progressive loss of muscle function. Here the authors characterize mitochondrial capacity and muscle function in young and older adults with similar habitual physical activity and also compared to older adults with exercise training or with physical impairment.L. GrevendonkN. J. ConnellC. McCrumC. E. FealyL. BiletY. M. H. BrulsJ. MevenkampV. B. Schrauwen-HinderlingJ. A. JörgensenE. Moonen-KornipsG. SchaartB. HavekesJ. de Vogel-van den BoschM. C. E. BragtK. MeijerP. SchrauwenJ. HoeksNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q L. Grevendonk N. J. Connell C. McCrum C. E. Fealy L. Bilet Y. M. H. Bruls J. Mevenkamp V. B. Schrauwen-Hinderling J. A. Jörgensen E. Moonen-Kornips G. Schaart B. Havekes J. de Vogel-van den Bosch M. C. E. Bragt K. Meijer P. Schrauwen J. Hoeks Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function |
| description |
Aging is associated with a progressive loss of muscle function. Here the authors characterize mitochondrial capacity and muscle function in young and older adults with similar habitual physical activity and also compared to older adults with exercise training or with physical impairment. |
| format |
article |
| author |
L. Grevendonk N. J. Connell C. McCrum C. E. Fealy L. Bilet Y. M. H. Bruls J. Mevenkamp V. B. Schrauwen-Hinderling J. A. Jörgensen E. Moonen-Kornips G. Schaart B. Havekes J. de Vogel-van den Bosch M. C. E. Bragt K. Meijer P. Schrauwen J. Hoeks |
| author_facet |
L. Grevendonk N. J. Connell C. McCrum C. E. Fealy L. Bilet Y. M. H. Bruls J. Mevenkamp V. B. Schrauwen-Hinderling J. A. Jörgensen E. Moonen-Kornips G. Schaart B. Havekes J. de Vogel-van den Bosch M. C. E. Bragt K. Meijer P. Schrauwen J. Hoeks |
| author_sort |
L. Grevendonk |
| title |
Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function |
| title_short |
Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function |
| title_full |
Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function |
| title_fullStr |
Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function |
| title_full_unstemmed |
Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function |
| title_sort |
impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/035190f53f0041ab9013b063d3712f34 |
| work_keys_str_mv |
AT lgrevendonk impactofagingandexerciseonskeletalmusclemitochondrialcapacityenergymetabolismandphysicalfunction AT njconnell impactofagingandexerciseonskeletalmusclemitochondrialcapacityenergymetabolismandphysicalfunction AT cmccrum impactofagingandexerciseonskeletalmusclemitochondrialcapacityenergymetabolismandphysicalfunction AT cefealy impactofagingandexerciseonskeletalmusclemitochondrialcapacityenergymetabolismandphysicalfunction AT lbilet impactofagingandexerciseonskeletalmusclemitochondrialcapacityenergymetabolismandphysicalfunction AT ymhbruls impactofagingandexerciseonskeletalmusclemitochondrialcapacityenergymetabolismandphysicalfunction AT jmevenkamp impactofagingandexerciseonskeletalmusclemitochondrialcapacityenergymetabolismandphysicalfunction AT vbschrauwenhinderling impactofagingandexerciseonskeletalmusclemitochondrialcapacityenergymetabolismandphysicalfunction AT jajorgensen impactofagingandexerciseonskeletalmusclemitochondrialcapacityenergymetabolismandphysicalfunction AT emoonenkornips impactofagingandexerciseonskeletalmusclemitochondrialcapacityenergymetabolismandphysicalfunction AT gschaart impactofagingandexerciseonskeletalmusclemitochondrialcapacityenergymetabolismandphysicalfunction AT bhavekes impactofagingandexerciseonskeletalmusclemitochondrialcapacityenergymetabolismandphysicalfunction AT jdevogelvandenbosch impactofagingandexerciseonskeletalmusclemitochondrialcapacityenergymetabolismandphysicalfunction AT mcebragt impactofagingandexerciseonskeletalmusclemitochondrialcapacityenergymetabolismandphysicalfunction AT kmeijer impactofagingandexerciseonskeletalmusclemitochondrialcapacityenergymetabolismandphysicalfunction AT pschrauwen impactofagingandexerciseonskeletalmusclemitochondrialcapacityenergymetabolismandphysicalfunction AT jhoeks impactofagingandexerciseonskeletalmusclemitochondrialcapacityenergymetabolismandphysicalfunction |
| _version_ |
1718377544554643456 |