The characteristics of choriocapillaris flow void in the unilateral polypoidal choroidal vasculopathy fellow eyes

Abstract To evaluate the morphological characteristics of flow void (FV) in the fellow eyes of the unilateral polypoidal choroidal vasculopathy (PCV). Fifty PCV fellow eyes (PCVF) and 31 age-matched normal ocular circulation controls were recruited in this retrospective study. The number of FV was a...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Huajui Wu, Yukinori Sugano, Kanako Itagaki, Akihito Kasai, Hiroaki Shintake, Tetsuju Sekiryu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/0352900ba0164fbdb36a29dc81c75d48
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0352900ba0164fbdb36a29dc81c75d48
record_format	dspace
spelling	oai:doaj.org-article:0352900ba0164fbdb36a29dc81c75d482021-12-05T12:12:12ZThe characteristics of choriocapillaris flow void in the unilateral polypoidal choroidal vasculopathy fellow eyes10.1038/s41598-021-02377-x2045-2322https://doaj.org/article/0352900ba0164fbdb36a29dc81c75d482021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-02377-xhttps://doaj.org/toc/2045-2322Abstract To evaluate the morphological characteristics of flow void (FV) in the fellow eyes of the unilateral polypoidal choroidal vasculopathy (PCV). Fifty PCV fellow eyes (PCVF) and 31 age-matched normal ocular circulation controls were recruited in this retrospective study. The number of FV was analyzed according to the size in a centered 5 × 5 mm swept source optical coherence tomography angiography scans. We used indocyanine green angiography images to determine whether choroidal vascular hyperpermeability (CVH) has occurred. For the PCVF, the prevalence rate of CVH was 70% (35 of 50) The number of FVs was significantly lower in 400–25,000 μm2 (P = 0.005), 400–500 μm2 (P = 0.001), 525–625 μm2 (P = 0.001) and 650–750 μm2 (P = 0.018). compared to the controls. And showed no difference in size from 775 to 1125 μm2 between the two groups. The area under the receiver operating characteristic curve of PCVF with CVH and controls was 0.94 (95% CI 0.88–1.00) (P < 0.001). We found that the number of small FVs was significantly lower in the PCV fellow eyes than that in the eyes with control group.Huajui WuYukinori SuganoKanako ItagakiAkihito KasaiHiroaki ShintakeTetsuju SekiryuNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Huajui Wu Yukinori Sugano Kanako Itagaki Akihito Kasai Hiroaki Shintake Tetsuju Sekiryu The characteristics of choriocapillaris flow void in the unilateral polypoidal choroidal vasculopathy fellow eyes
description	Abstract To evaluate the morphological characteristics of flow void (FV) in the fellow eyes of the unilateral polypoidal choroidal vasculopathy (PCV). Fifty PCV fellow eyes (PCVF) and 31 age-matched normal ocular circulation controls were recruited in this retrospective study. The number of FV was analyzed according to the size in a centered 5 × 5 mm swept source optical coherence tomography angiography scans. We used indocyanine green angiography images to determine whether choroidal vascular hyperpermeability (CVH) has occurred. For the PCVF, the prevalence rate of CVH was 70% (35 of 50) The number of FVs was significantly lower in 400–25,000 μm2 (P = 0.005), 400–500 μm2 (P = 0.001), 525–625 μm2 (P = 0.001) and 650–750 μm2 (P = 0.018). compared to the controls. And showed no difference in size from 775 to 1125 μm2 between the two groups. The area under the receiver operating characteristic curve of PCVF with CVH and controls was 0.94 (95% CI 0.88–1.00) (P < 0.001). We found that the number of small FVs was significantly lower in the PCV fellow eyes than that in the eyes with control group.
format	article
author	Huajui Wu Yukinori Sugano Kanako Itagaki Akihito Kasai Hiroaki Shintake Tetsuju Sekiryu
author_facet	Huajui Wu Yukinori Sugano Kanako Itagaki Akihito Kasai Hiroaki Shintake Tetsuju Sekiryu
author_sort	Huajui Wu
title	The characteristics of choriocapillaris flow void in the unilateral polypoidal choroidal vasculopathy fellow eyes
title_short	The characteristics of choriocapillaris flow void in the unilateral polypoidal choroidal vasculopathy fellow eyes
title_full	The characteristics of choriocapillaris flow void in the unilateral polypoidal choroidal vasculopathy fellow eyes
title_fullStr	The characteristics of choriocapillaris flow void in the unilateral polypoidal choroidal vasculopathy fellow eyes
title_full_unstemmed	The characteristics of choriocapillaris flow void in the unilateral polypoidal choroidal vasculopathy fellow eyes
title_sort	characteristics of choriocapillaris flow void in the unilateral polypoidal choroidal vasculopathy fellow eyes
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0352900ba0164fbdb36a29dc81c75d48
work_keys_str_mv	AT huajuiwu thecharacteristicsofchoriocapillarisflowvoidintheunilateralpolypoidalchoroidalvasculopathyfelloweyes AT yukinorisugano thecharacteristicsofchoriocapillarisflowvoidintheunilateralpolypoidalchoroidalvasculopathyfelloweyes AT kanakoitagaki thecharacteristicsofchoriocapillarisflowvoidintheunilateralpolypoidalchoroidalvasculopathyfelloweyes AT akihitokasai thecharacteristicsofchoriocapillarisflowvoidintheunilateralpolypoidalchoroidalvasculopathyfelloweyes AT hiroakishintake thecharacteristicsofchoriocapillarisflowvoidintheunilateralpolypoidalchoroidalvasculopathyfelloweyes AT tetsujusekiryu thecharacteristicsofchoriocapillarisflowvoidintheunilateralpolypoidalchoroidalvasculopathyfelloweyes AT huajuiwu characteristicsofchoriocapillarisflowvoidintheunilateralpolypoidalchoroidalvasculopathyfelloweyes AT yukinorisugano characteristicsofchoriocapillarisflowvoidintheunilateralpolypoidalchoroidalvasculopathyfelloweyes AT kanakoitagaki characteristicsofchoriocapillarisflowvoidintheunilateralpolypoidalchoroidalvasculopathyfelloweyes AT akihitokasai characteristicsofchoriocapillarisflowvoidintheunilateralpolypoidalchoroidalvasculopathyfelloweyes AT hiroakishintake characteristicsofchoriocapillarisflowvoidintheunilateralpolypoidalchoroidalvasculopathyfelloweyes AT tetsujusekiryu characteristicsofchoriocapillarisflowvoidintheunilateralpolypoidalchoroidalvasculopathyfelloweyes
_version_	1718372113757241344

The characteristics of choriocapillaris flow void in the unilateral polypoidal choroidal vasculopathy fellow eyes

Ejemplares similares