Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival

Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival

Protein kinases are fundamental in cellular signalling required for Leishmania survival throughout the life cycle. Here, Baker and Catta-Preta et al. report on a kinome-wide functional study in Leishmania mexicana to define protein kinases with roles in life cycle transition.

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Detalles Bibliográficos
Autores principales: N. Baker, C. M. C. Catta-Preta, R. Neish, J. Sadlova, B. Powell, E. V. C. Alves-Ferreira, V. Geoghegan, J. B. T. Carnielli, K. Newling, C. Hughes, B. Vojtkova, J. Anand, A. Mihut, P. B. Walrad, L. G. Wilson, J. W. Pitchford, P. Volf, J. C. Mottram
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
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Acceso en línea:https://doaj.org/article/035f2b3b482f4ffdb928ae592833e43e
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Descripción
Sumario:Protein kinases are fundamental in cellular signalling required for Leishmania survival throughout the life cycle. Here, Baker and Catta-Preta et al. report on a kinome-wide functional study in Leishmania mexicana to define protein kinases with roles in life cycle transition.

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