Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival
Protein kinases are fundamental in cellular signalling required for Leishmania survival throughout the life cycle. Here, Baker and Catta-Preta et al. report on a kinome-wide functional study in Leishmania mexicana to define protein kinases with roles in life cycle transition.
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Nature Portfolio
2021
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| Acceso en línea: | https://doaj.org/article/035f2b3b482f4ffdb928ae592833e43e |
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oai:doaj.org-article:035f2b3b482f4ffdb928ae592833e43e2021-12-02T10:59:18ZSystematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival10.1038/s41467-021-21360-82041-1723https://doaj.org/article/035f2b3b482f4ffdb928ae592833e43e2021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21360-8https://doaj.org/toc/2041-1723Protein kinases are fundamental in cellular signalling required for Leishmania survival throughout the life cycle. Here, Baker and Catta-Preta et al. report on a kinome-wide functional study in Leishmania mexicana to define protein kinases with roles in life cycle transition.N. BakerC. M. C. Catta-PretaR. NeishJ. SadlovaB. PowellE. V. C. Alves-FerreiraV. GeogheganJ. B. T. CarnielliK. NewlingC. HughesB. VojtkovaJ. AnandA. MihutP. B. WalradL. G. WilsonJ. W. PitchfordP. VolfJ. C. MottramNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q N. Baker C. M. C. Catta-Preta R. Neish J. Sadlova B. Powell E. V. C. Alves-Ferreira V. Geoghegan J. B. T. Carnielli K. Newling C. Hughes B. Vojtkova J. Anand A. Mihut P. B. Walrad L. G. Wilson J. W. Pitchford P. Volf J. C. Mottram Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival |
| description |
Protein kinases are fundamental in cellular signalling required for Leishmania survival throughout the life cycle. Here, Baker and Catta-Preta et al. report on a kinome-wide functional study in Leishmania mexicana to define protein kinases with roles in life cycle transition. |
| format |
article |
| author |
N. Baker C. M. C. Catta-Preta R. Neish J. Sadlova B. Powell E. V. C. Alves-Ferreira V. Geoghegan J. B. T. Carnielli K. Newling C. Hughes B. Vojtkova J. Anand A. Mihut P. B. Walrad L. G. Wilson J. W. Pitchford P. Volf J. C. Mottram |
| author_facet |
N. Baker C. M. C. Catta-Preta R. Neish J. Sadlova B. Powell E. V. C. Alves-Ferreira V. Geoghegan J. B. T. Carnielli K. Newling C. Hughes B. Vojtkova J. Anand A. Mihut P. B. Walrad L. G. Wilson J. W. Pitchford P. Volf J. C. Mottram |
| author_sort |
N. Baker |
| title |
Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival |
| title_short |
Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival |
| title_full |
Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival |
| title_fullStr |
Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival |
| title_full_unstemmed |
Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival |
| title_sort |
systematic functional analysis of leishmania protein kinases identifies regulators of differentiation or survival |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/035f2b3b482f4ffdb928ae592833e43e |
| work_keys_str_mv |
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| _version_ |
1718396332461260800 |