SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3–LAR adhesion

SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3–LAR adhesion

Synaptic adhesion molecules regulate synapse development and function by both cis and trans-interactions. Here, Lie et al. show that postsynaptic SALM4 regulates excitatory synapse numbers by cisinhibition of the SALM3-LAR transynaptic interaction.

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Autores principales: Eunkyung Lie, Ji Seung Ko, Su-Yeon Choi, Junyeop Daniel Roh, Yi Sul Cho, Ran Noh, Doyoun Kim, Yan Li, Hyeyeon Kang, Tae-Yong Choi, Jungyong Nam, Won Mah, Dongmin Lee, Seong-Gyu Lee, Ho Min Kim, Hyun Kim, Se-Young Choi, Ji Won Um, Myoung-Goo Kang, Yong Chul Bae, Jaewon Ko, Eunjoon Kim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/0361ae92e2464f95885cd28b8f1c0ee4
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spelling oai:doaj.org-article:0361ae92e2464f95885cd28b8f1c0ee42021-12-02T17:31:35ZSALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3–LAR adhesion10.1038/ncomms123282041-1723https://doaj.org/article/0361ae92e2464f95885cd28b8f1c0ee42016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12328https://doaj.org/toc/2041-1723Synaptic adhesion molecules regulate synapse development and function by both cis and trans-interactions. Here, Lie et al. show that postsynaptic SALM4 regulates excitatory synapse numbers by cisinhibition of the SALM3-LAR transynaptic interaction.Eunkyung LieJi Seung KoSu-Yeon ChoiJunyeop Daniel RohYi Sul ChoRan NohDoyoun KimYan LiHyeyeon KangTae-Yong ChoiJungyong NamWon MahDongmin LeeSeong-Gyu LeeHo Min KimHyun KimSe-Young ChoiJi Won UmMyoung-Goo KangYong Chul BaeJaewon KoEunjoon KimNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Eunkyung Lie
Ji Seung Ko
Su-Yeon Choi
Junyeop Daniel Roh
Yi Sul Cho
Ran Noh
Doyoun Kim
Yan Li
Hyeyeon Kang
Tae-Yong Choi
Jungyong Nam
Won Mah
Dongmin Lee
Seong-Gyu Lee
Ho Min Kim
Hyun Kim
Se-Young Choi
Ji Won Um
Myoung-Goo Kang
Yong Chul Bae
Jaewon Ko
Eunjoon Kim
SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3–LAR adhesion
description Synaptic adhesion molecules regulate synapse development and function by both cis and trans-interactions. Here, Lie et al. show that postsynaptic SALM4 regulates excitatory synapse numbers by cisinhibition of the SALM3-LAR transynaptic interaction.
format article
author Eunkyung Lie
Ji Seung Ko
Su-Yeon Choi
Junyeop Daniel Roh
Yi Sul Cho
Ran Noh
Doyoun Kim
Yan Li
Hyeyeon Kang
Tae-Yong Choi
Jungyong Nam
Won Mah
Dongmin Lee
Seong-Gyu Lee
Ho Min Kim
Hyun Kim
Se-Young Choi
Ji Won Um
Myoung-Goo Kang
Yong Chul Bae
Jaewon Ko
Eunjoon Kim
author_facet Eunkyung Lie
Ji Seung Ko
Su-Yeon Choi
Junyeop Daniel Roh
Yi Sul Cho
Ran Noh
Doyoun Kim
Yan Li
Hyeyeon Kang
Tae-Yong Choi
Jungyong Nam
Won Mah
Dongmin Lee
Seong-Gyu Lee
Ho Min Kim
Hyun Kim
Se-Young Choi
Ji Won Um
Myoung-Goo Kang
Yong Chul Bae
Jaewon Ko
Eunjoon Kim
author_sort Eunkyung Lie
title SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3–LAR adhesion
title_short SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3–LAR adhesion
title_full SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3–LAR adhesion
title_fullStr SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3–LAR adhesion
title_full_unstemmed SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3–LAR adhesion
title_sort salm4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic salm3–lar adhesion
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/0361ae92e2464f95885cd28b8f1c0ee4
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