Protein-responsive protein release of supramolecular/polymer hydrogel composite integrating enzyme activation systems

Responsive hydrogels are of interest for diagnostic and controlled drug release applications. Here, the authors report on the design of a hydrogel with protein triggered release of an embedded protein through recovery of enzyme activity and subsequent degradation of supramolecular fibers.

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Autores principales: Hajime Shigemitsu, Ryou Kubota, Keisuke Nakamura, Tomonobu Matsuzaki, Saori Minami, Takuma Aoyama, Kenji Urayama, Itaru Hamachi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/036386edb2de4ec6a7aab2140763fdac
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