Cytoplasmic Skp2 expression is associated with p-Akt1 and predicts poor prognosis in human breast carcinomas.

<h4>Background</h4>S-phase kinase protein 2 (Skp2), an oncogenic protein, is a key regulator in different cellular and molecular processes, through ubiquitin-proteasome degradation pathway. Increased levels of Skp2 are observed in various types of cancer and associated with poor prognosi...

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Auteurs principaux: Jing Liu, Xiao-Long Wei, Wen-He Huang, Chun-Fa Chen, Jing-Wen Bai, Guo-Jun Zhang
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2012
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Accès en ligne:https://doaj.org/article/0364db54e09a4be38bb799f7024ea95b
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