Characterisation of genome-wide PLZF/RARA target genes.

Characterisation of genome-wide PLZF/RARA target genes.

The PLZF/RARA fusion protein generated by the t(11;17)(q23;q21) translocation in acute promyelocytic leukaemia (APL) is believed to act as an oncogenic transcriptional regulator recruiting epigenetic factors to genes important for its transforming potential. However, molecular mechanisms associated...

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Auteurs principaux: Salvatore Spicuglia, Christelle Vincent-Fabert, Touati Benoukraf, Guillaume Tibéri, Andrew J Saurin, Joaquin Zacarias-Cabeza, David Grimwade, Ken Mills, Boris Calmels, François Bertucci, Michael Sieweke, Pierre Ferrier, Estelle Duprez
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/036763c1e99d4a398ec92fd73ef0dbbb
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https://doaj.org/article/036763c1e99d4a398ec92fd73ef0dbbb

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