Evolution of multidrug resistance during Staphylococcus aureus infection involves mutation of the essential two component regulator WalKR.

Antimicrobial resistance in Staphylococcus aureus is a major public health threat, compounded by emergence of strains with resistance to vancomycin and daptomycin, both last line antimicrobials. Here we have performed high throughput DNA sequencing and comparative genomics for five clinical pairs of...

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Main Authors: Benjamin P Howden, Christopher R E McEvoy, David L Allen, Kyra Chua, Wei Gao, Paul F Harrison, Jan Bell, Geoffrey Coombs, Vicki Bennett-Wood, Jessica L Porter, Roy Robins-Browne, John K Davies, Torsten Seemann, Timothy P Stinear
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
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Online Access:https://doaj.org/article/0368cd80d7ff4eb2b613194047802cfc
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