CD13 orients the apical-basal polarity axis necessary for lumen formation

Epithelial cells that organise into structures that contain a lumen are polarised. Here, the authors show that the short intracellular domain of transmembrane protein CD13 is required to capture endosomes at the apical site and is required for the polarisation of cells.

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Auteurs principaux: Li-Ting Wang, Abira Rajah, Claire M. Brown, Luke McCaffrey
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/036f5b17608448fa948f9d7a338d3066
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