A stable and reproducible human blood-brain barrier model derived from hematopoietic stem cells.

A stable and reproducible human blood-brain barrier model derived from hematopoietic stem cells.

The human blood brain barrier (BBB) is a selective barrier formed by human brain endothelial cells (hBECs), which is important to ensure adequate neuronal function and protect the central nervous system (CNS) from disease. The development of human in vitro BBB models is thus of utmost importance for...

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Autores principales: Romeo Cecchelli, Sezin Aday, Emmanuel Sevin, Catarina Almeida, Maxime Culot, Lucie Dehouck, Caroline Coisne, Britta Engelhardt, Marie-Pierre Dehouck, Lino Ferreira
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/038b8b5427fb4a6e9883e104b067d9ae
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