A comparison of the vancomycin calcium sulfate implantation versus fenestration decompression for the treatment of sclerosing osteomyelitis

Abstract Objective To compare the clinical efficacy of vancomycin calcium sulfate implantation and fenestration decompression in the treatment of sclerosing osteomyelitis. Method A retrospective analysis for 46 cases of sclerosing osteomyelitis were admitted to our department between June 2010 to Ju...

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Autores principales: Haotian Hua, Xinwei Wang, Jiangang Guo, Lei Zhang, Zairan Guo, Jiangfei Chen
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Lenguaje:EN
Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/03966273cbf04ad4b0b929cb5a3413b7
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spelling oai:doaj.org-article:03966273cbf04ad4b0b929cb5a3413b72021-12-05T12:18:26ZA comparison of the vancomycin calcium sulfate implantation versus fenestration decompression for the treatment of sclerosing osteomyelitis10.1186/s12891-021-04881-71471-2474https://doaj.org/article/03966273cbf04ad4b0b929cb5a3413b72021-11-01T00:00:00Zhttps://doi.org/10.1186/s12891-021-04881-7https://doaj.org/toc/1471-2474Abstract Objective To compare the clinical efficacy of vancomycin calcium sulfate implantation and fenestration decompression in the treatment of sclerosing osteomyelitis. Method A retrospective analysis for 46 cases of sclerosing osteomyelitis were admitted to our department between June 2010 to June 2020. Twenty-one patients were treated with fenestration decompression, twenty-five patients were treated with vancomycin calcium sulfate implantation. The postoperative hospital stay, days of drainage tube placement, visual analogue scale scores, C-reactive protein and erythrocyte sedimentation rate were compared between the two groups. Results The visual analogue scale scores of both groups were significantly lower than before treatment (p < 0.05), but the difference between them was not statistically significant. Patients treated by vancomycin calcium sulfate implantation had shorter postoperative hospital stay and days of drainage tube placement compared to those treated by fenestration decompression (p < 0.05). C-reactive protein and erythrocyte sedimentation rate in both groups were significantly lower than before treatment, but the improvement effect of vancomycin calcium sulfate implantation was better (p < 0.05). Conclusion Both treatment methods can relieve pain effectively. Compared with fenestration decompression, vancomycin calcium sulfate implantation can shorten the treatment time effectively, control the infection better.Haotian HuaXinwei WangJiangang GuoLei ZhangZairan GuoJiangfei ChenBMCarticleVancomycin calcium sulfate implantation (VCSI)Fenestration decompression (FD)Sclerosing osteomyelitisPainDiseases of the musculoskeletal systemRC925-935ENBMC Musculoskeletal Disorders, Vol 22, Iss 1, Pp 1-7 (2021)
institution DOAJ
collection DOAJ
language EN
topic Vancomycin calcium sulfate implantation (VCSI)
Fenestration decompression (FD)
Sclerosing osteomyelitis
Pain
Diseases of the musculoskeletal system
RC925-935
spellingShingle Vancomycin calcium sulfate implantation (VCSI)
Fenestration decompression (FD)
Sclerosing osteomyelitis
Pain
Diseases of the musculoskeletal system
RC925-935
Haotian Hua
Xinwei Wang
Jiangang Guo
Lei Zhang
Zairan Guo
Jiangfei Chen
A comparison of the vancomycin calcium sulfate implantation versus fenestration decompression for the treatment of sclerosing osteomyelitis
description Abstract Objective To compare the clinical efficacy of vancomycin calcium sulfate implantation and fenestration decompression in the treatment of sclerosing osteomyelitis. Method A retrospective analysis for 46 cases of sclerosing osteomyelitis were admitted to our department between June 2010 to June 2020. Twenty-one patients were treated with fenestration decompression, twenty-five patients were treated with vancomycin calcium sulfate implantation. The postoperative hospital stay, days of drainage tube placement, visual analogue scale scores, C-reactive protein and erythrocyte sedimentation rate were compared between the two groups. Results The visual analogue scale scores of both groups were significantly lower than before treatment (p < 0.05), but the difference between them was not statistically significant. Patients treated by vancomycin calcium sulfate implantation had shorter postoperative hospital stay and days of drainage tube placement compared to those treated by fenestration decompression (p < 0.05). C-reactive protein and erythrocyte sedimentation rate in both groups were significantly lower than before treatment, but the improvement effect of vancomycin calcium sulfate implantation was better (p < 0.05). Conclusion Both treatment methods can relieve pain effectively. Compared with fenestration decompression, vancomycin calcium sulfate implantation can shorten the treatment time effectively, control the infection better.
format article
author Haotian Hua
Xinwei Wang
Jiangang Guo
Lei Zhang
Zairan Guo
Jiangfei Chen
author_facet Haotian Hua
Xinwei Wang
Jiangang Guo
Lei Zhang
Zairan Guo
Jiangfei Chen
author_sort Haotian Hua
title A comparison of the vancomycin calcium sulfate implantation versus fenestration decompression for the treatment of sclerosing osteomyelitis
title_short A comparison of the vancomycin calcium sulfate implantation versus fenestration decompression for the treatment of sclerosing osteomyelitis
title_full A comparison of the vancomycin calcium sulfate implantation versus fenestration decompression for the treatment of sclerosing osteomyelitis
title_fullStr A comparison of the vancomycin calcium sulfate implantation versus fenestration decompression for the treatment of sclerosing osteomyelitis
title_full_unstemmed A comparison of the vancomycin calcium sulfate implantation versus fenestration decompression for the treatment of sclerosing osteomyelitis
title_sort comparison of the vancomycin calcium sulfate implantation versus fenestration decompression for the treatment of sclerosing osteomyelitis
publisher BMC
publishDate 2021
url https://doaj.org/article/03966273cbf04ad4b0b929cb5a3413b7
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