Nanoantibiotics: strategic assets in the fight against drug- resistant superbugs

Chandni Khurana, Bhupendra Chudasama Laboratory of Nanomedicine, School of Physics and Materials Science, Thapar University, Patiala, Punjab, India Abstract: Antimicrobial characteristics of metals reveal that Ag despite its economic constraints remains the most popular antibiotic agent. Antimicro...

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Autores principales:	Khurana C, Chudasama B
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Nanoantibiotics silver copper drug resistance Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/03a1b7711f54409c9f916cd00d853e84
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spelling	oai:doaj.org-article:03a1b7711f54409c9f916cd00d853e842021-12-02T07:45:56ZNanoantibiotics: strategic assets in the fight against drug- resistant superbugs1178-2013https://doaj.org/article/03a1b7711f54409c9f916cd00d853e842018-03-01T00:00:00Zhttps://www.dovepress.com/nanoantibiotics-strategic-assets-in-the-fight-against-drug-resistant-s-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Chandni Khurana, Bhupendra Chudasama Laboratory of Nanomedicine, School of Physics and Materials Science, Thapar University, Patiala, Punjab, India Abstract: Antimicrobial characteristics of metals reveal that Ag despite its economic constraints remains the most popular antibiotic agent. Antimicrobial characteristics of copper nanoparticles (CNPs) are not well understood. To our knowledge, no systematic comparative study on microbial properties of silver nanoparticles (SNPs) and CNPs exists. In this article, a comparative study on microbial properties of engineered metal nanoantibiotics against clinically important strains has been attempted. Our results indicate that biocidal activities of CNPs are better than SNPs. Minimum inhibitory concentration (MIC) values of CNPs are 10 times lower than the corresponding MICs of SNPs. These improved biocidal activities of CNPs would make it affordable and potent nontraditional antibiotics against which microbes are least susceptible to develop any drug resistance. Keywords: antibiotics, silver, copper, nanoparticlesKhurana CChudasama BDove Medical PressarticleNanoantibioticssilvercopperdrug resistanceMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 13, Pp 3-6 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Nanoantibiotics silver copper drug resistance Medicine (General) R5-920
spellingShingle	Nanoantibiotics silver copper drug resistance Medicine (General) R5-920 Khurana C Chudasama B Nanoantibiotics: strategic assets in the fight against drug- resistant superbugs
description	Chandni Khurana, Bhupendra Chudasama Laboratory of Nanomedicine, School of Physics and Materials Science, Thapar University, Patiala, Punjab, India Abstract: Antimicrobial characteristics of metals reveal that Ag despite its economic constraints remains the most popular antibiotic agent. Antimicrobial characteristics of copper nanoparticles (CNPs) are not well understood. To our knowledge, no systematic comparative study on microbial properties of silver nanoparticles (SNPs) and CNPs exists. In this article, a comparative study on microbial properties of engineered metal nanoantibiotics against clinically important strains has been attempted. Our results indicate that biocidal activities of CNPs are better than SNPs. Minimum inhibitory concentration (MIC) values of CNPs are 10 times lower than the corresponding MICs of SNPs. These improved biocidal activities of CNPs would make it affordable and potent nontraditional antibiotics against which microbes are least susceptible to develop any drug resistance. Keywords: antibiotics, silver, copper, nanoparticles
format	article
author	Khurana C Chudasama B
author_facet	Khurana C Chudasama B
author_sort	Khurana C
title	Nanoantibiotics: strategic assets in the fight against drug- resistant superbugs
title_short	Nanoantibiotics: strategic assets in the fight against drug- resistant superbugs
title_full	Nanoantibiotics: strategic assets in the fight against drug- resistant superbugs
title_fullStr	Nanoantibiotics: strategic assets in the fight against drug- resistant superbugs
title_full_unstemmed	Nanoantibiotics: strategic assets in the fight against drug- resistant superbugs
title_sort	nanoantibiotics: strategic assets in the fight against drug- resistant superbugs
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/03a1b7711f54409c9f916cd00d853e84
work_keys_str_mv	AT khuranac nanoantibioticsstrategicassetsinthefightagainstdrugresistantsuperbugs AT chudasamab nanoantibioticsstrategicassetsinthefightagainstdrugresistantsuperbugs
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Nanoantibiotics: strategic assets in the fight against drug- resistant superbugs

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