Both functional LTbeta receptor and TNF receptor 2 are required for the development of experimental cerebral malaria.

Both functional LTbeta receptor and TNF receptor 2 are required for the development of experimental cerebral malaria.

<h4>Background</h4>TNF-related lymphotoxin alpha (LTalpha) is essential for the development of Plasmodium berghei ANKA (PbA)-induced experimental cerebral malaria (ECM). The pathway involved has been attributed to TNFR2. Here we show a second arm of LTalpha-signaling essential for ECM de...

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Autores principales: Dieudonnée Togbe, Paulo Loureiro de Sousa, Mathilde Fauconnier, Victorine Boissay, Lizette Fick, Stefanie Scheu, Klaus Pfeffer, Robert Menard, Georges E Grau, Bich-Thuy Doan, Jean Claude Beloeil, Laurent Renia, Anna M Hansen, Helen J Ball, Nicholas H Hunt, Bernhard Ryffel, Valerie F J Quesniaux
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2008
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/03a2d237b3284307b66e4c9f4bb6006d
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