Deletion of Cytoplasmic Double-Stranded RNA Sensors Does Not Uncover Viral Small Interfering RNA Production in Human Cells

ABSTRACT Antiviral immunity in insects and plants is mediated by the RNA interference (RNAi) pathway in which viral long double-stranded RNA (dsRNA) is processed into small interfering RNAs (siRNAs) by Dicer enzymes. Although this pathway is evolutionarily conserved, its involvement in antiviral def...

Full description

Saved in:
Bibliographic Details
Main Authors: Susan Schuster, Lotte E. Tholen, Gijs J. Overheul, Frank J. M. van Kuppeveld, Ronald P. van Rij
Format: article
Language:EN
Published: American Society for Microbiology 2017
Subjects:
Online Access:https://doaj.org/article/03a486fa50d143b2871fcedda04b4d12
Tags: Add Tag
No Tags, Be the first to tag this record!