Surface expression and subunit specific control of steady protein levels by the Kv7.2 helix A-B linker.

Surface expression and subunit specific control of steady protein levels by the Kv7.2 helix A-B linker.

Kv7.2 and Kv7.3 are the main components of the neuronal voltage-dependent M-current, which is a subthreshold potassium conductance that exerts an important control on neuronal excitability. Despite their predominantly intracellular distribution, these channels must reach the plasma membrane in order...

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Main Authors: Paloma Aivar, Juncal Fernández-Orth, Carolina Gomis-Perez, Araitz Alberdi, Alessandro Alaimo, Manuel S Rodríguez, Teresa Giraldez, Pablo Miranda, Pilar Areso, Alvaro Villarroel
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/03b2e166e5c6489d990b8c77d87459e1
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