Severe hyponatremia due to paraneoplastic syndrome of inappropriate antidiuretic hormone secretion in non-small cell lung carcinoma transforming to small cell lung carcinoma during treatment with immune checkpoint inhibitor

This is the first case described of transformation from EGFR wild-type non-small cell lung cancer (NSCLC) to small cell lung cancer (SCLC) during immunotherapy presenting with severe hyponatremia due to paraneoplastic syndrome of inappropriate antidiuretic hormone secretion.

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Autores principales:	Vicky Mai, Sylvain Trahan, Sylvain Pagé, Mathieu Simon, Catherine Labbé
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	EGFR wild-type NSCLC Transformation to SCLC Immunotherapy SIADH, resistance mechanism Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/03b3bc7627ce46a590c6dee520187bcc
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spelling	oai:doaj.org-article:03b3bc7627ce46a590c6dee520187bcc2021-11-04T04:42:19ZSevere hyponatremia due to paraneoplastic syndrome of inappropriate antidiuretic hormone secretion in non-small cell lung carcinoma transforming to small cell lung carcinoma during treatment with immune checkpoint inhibitor2666-621910.1016/j.cpccr.2021.100125https://doaj.org/article/03b3bc7627ce46a590c6dee520187bcc2021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2666621921000739https://doaj.org/toc/2666-6219This is the first case described of transformation from EGFR wild-type non-small cell lung cancer (NSCLC) to small cell lung cancer (SCLC) during immunotherapy presenting with severe hyponatremia due to paraneoplastic syndrome of inappropriate antidiuretic hormone secretion.Vicky MaiSylvain TrahanSylvain PagéMathieu SimonCatherine LabbéElsevierarticleEGFR wild-type NSCLCTransformation to SCLCImmunotherapySIADH, resistance mechanismNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENCurrent Problems in Cancer: Case Reports, Vol 4, Iss , Pp 100125- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	EGFR wild-type NSCLC Transformation to SCLC Immunotherapy SIADH, resistance mechanism Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	EGFR wild-type NSCLC Transformation to SCLC Immunotherapy SIADH, resistance mechanism Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Vicky Mai Sylvain Trahan Sylvain Pagé Mathieu Simon Catherine Labbé Severe hyponatremia due to paraneoplastic syndrome of inappropriate antidiuretic hormone secretion in non-small cell lung carcinoma transforming to small cell lung carcinoma during treatment with immune checkpoint inhibitor
description	This is the first case described of transformation from EGFR wild-type non-small cell lung cancer (NSCLC) to small cell lung cancer (SCLC) during immunotherapy presenting with severe hyponatremia due to paraneoplastic syndrome of inappropriate antidiuretic hormone secretion.
format	article
author	Vicky Mai Sylvain Trahan Sylvain Pagé Mathieu Simon Catherine Labbé
author_facet	Vicky Mai Sylvain Trahan Sylvain Pagé Mathieu Simon Catherine Labbé
author_sort	Vicky Mai
title	Severe hyponatremia due to paraneoplastic syndrome of inappropriate antidiuretic hormone secretion in non-small cell lung carcinoma transforming to small cell lung carcinoma during treatment with immune checkpoint inhibitor
title_short	Severe hyponatremia due to paraneoplastic syndrome of inappropriate antidiuretic hormone secretion in non-small cell lung carcinoma transforming to small cell lung carcinoma during treatment with immune checkpoint inhibitor
title_full	Severe hyponatremia due to paraneoplastic syndrome of inappropriate antidiuretic hormone secretion in non-small cell lung carcinoma transforming to small cell lung carcinoma during treatment with immune checkpoint inhibitor
title_fullStr	Severe hyponatremia due to paraneoplastic syndrome of inappropriate antidiuretic hormone secretion in non-small cell lung carcinoma transforming to small cell lung carcinoma during treatment with immune checkpoint inhibitor
title_full_unstemmed	Severe hyponatremia due to paraneoplastic syndrome of inappropriate antidiuretic hormone secretion in non-small cell lung carcinoma transforming to small cell lung carcinoma during treatment with immune checkpoint inhibitor
title_sort	severe hyponatremia due to paraneoplastic syndrome of inappropriate antidiuretic hormone secretion in non-small cell lung carcinoma transforming to small cell lung carcinoma during treatment with immune checkpoint inhibitor
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/03b3bc7627ce46a590c6dee520187bcc
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Severe hyponatremia due to paraneoplastic syndrome of inappropriate antidiuretic hormone secretion in non-small cell lung carcinoma transforming to small cell lung carcinoma during treatment with immune checkpoint inhibitor

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