Establishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics

Nanoparticle applications are limited by insufficient understanding of physiochemical properties on in vivo disposition. Here, the authors explore the influence of size, surface chemistry and administration on the biodisposition of mesoporous silica nanoparticles using image-based pharmacokinetics.

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Autores principales:	Prashant Dogra, Natalie L. Adolphi, Zhihui Wang, Yu-Shen Lin, Kimberly S. Butler, Paul N. Durfee, Jonas G. Croissant, Achraf Noureddine, Eric N. Coker, Elaine L. Bearer, Vittorio Cristini, C. Jeffrey Brinker
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/03c874c2055f48d9bf522fd89ec06520
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spelling	oai:doaj.org-article:03c874c2055f48d9bf522fd89ec065202021-12-02T15:34:41ZEstablishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics10.1038/s41467-018-06730-z2041-1723https://doaj.org/article/03c874c2055f48d9bf522fd89ec065202018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06730-zhttps://doaj.org/toc/2041-1723Nanoparticle applications are limited by insufficient understanding of physiochemical properties on in vivo disposition. Here, the authors explore the influence of size, surface chemistry and administration on the biodisposition of mesoporous silica nanoparticles using image-based pharmacokinetics.Prashant DograNatalie L. AdolphiZhihui WangYu-Shen LinKimberly S. ButlerPaul N. DurfeeJonas G. CroissantAchraf NoureddineEric N. CokerElaine L. BearerVittorio CristiniC. Jeffrey BrinkerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Prashant Dogra Natalie L. Adolphi Zhihui Wang Yu-Shen Lin Kimberly S. Butler Paul N. Durfee Jonas G. Croissant Achraf Noureddine Eric N. Coker Elaine L. Bearer Vittorio Cristini C. Jeffrey Brinker Establishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics
description	Nanoparticle applications are limited by insufficient understanding of physiochemical properties on in vivo disposition. Here, the authors explore the influence of size, surface chemistry and administration on the biodisposition of mesoporous silica nanoparticles using image-based pharmacokinetics.
format	article
author	Prashant Dogra Natalie L. Adolphi Zhihui Wang Yu-Shen Lin Kimberly S. Butler Paul N. Durfee Jonas G. Croissant Achraf Noureddine Eric N. Coker Elaine L. Bearer Vittorio Cristini C. Jeffrey Brinker
author_facet	Prashant Dogra Natalie L. Adolphi Zhihui Wang Yu-Shen Lin Kimberly S. Butler Paul N. Durfee Jonas G. Croissant Achraf Noureddine Eric N. Coker Elaine L. Bearer Vittorio Cristini C. Jeffrey Brinker
author_sort	Prashant Dogra
title	Establishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics
title_short	Establishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics
title_full	Establishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics
title_fullStr	Establishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics
title_full_unstemmed	Establishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics
title_sort	establishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/03c874c2055f48d9bf522fd89ec06520
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Establishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics

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