Development and validation of a screening instrument for bipolar spectrum disorder: The Mood Disorder Questionnaire Thai version

Punjaporn Waleeprakhon,1 Pichai Ittasakul,1 Manote Lotrakul,1 Pattarabhorn Wisajun,1 Sudawan Jullagate,1 Terence A Ketter2 1Department of Psychiatry, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; 2Department of Psychiatry and Behavioral Sciences, Stanford Univer...

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Autores principales:	Waleeprakhon P, Ittasakul P, Lotrakul M, Wisajun P, Jullagate S, Ketter TA
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/03cf749dc515434f827089341d388789
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spelling	oai:doaj.org-article:03cf749dc515434f827089341d3887892021-12-02T08:05:19ZDevelopment and validation of a screening instrument for bipolar spectrum disorder: The Mood Disorder Questionnaire Thai version1178-2021https://doaj.org/article/03cf749dc515434f827089341d3887892014-08-01T00:00:00Zhttp://www.dovepress.com/development-and-validation-of-a-screening-instrument-for-bipolar-spect-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021 Punjaporn Waleeprakhon,1 Pichai Ittasakul,1 Manote Lotrakul,1 Pattarabhorn Wisajun,1 Sudawan Jullagate,1 Terence A Ketter2 1Department of Psychiatry, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; 2Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA Background: The Mood Disorder Questionnaire (MDQ) has been translated to many languages and has been used in many countries as a screening instrument for bipolar disorder. The main objective of this study was to evaluate validity of the Thai version of the MDQ as a screening instrument for bipolar disorder in a psychiatric outpatient sample, and to determine its optimum question #1 item threshold value for bipolar disorder.Methods: The English language Mood Disorder Questionnaire (MDQ) was translated into Thai. The process involved back-translation, cross-cultural adaptation, field testing of the prefinal version, as well as final adjustments. Two hundred and fifty major depressive disorder outpatients were further assessed by the Thai version of the MDQ and the Thai version of the Mini International Neuropsychiatric Interview (MINI). During the assessment, reliability and validity analyses, and receiver operating characteristic curve (ROC) analysis were performed.Results: The Thai version of the MDQ screening had adequate internal consistency (Cronbach’s alpha =0.791, omega total =0.68, and omega hierarchical =0.69). The optimal question #1 item threshold value was at least five positive items, which yielded adequate sensitivity (76.5%), specificity (72.7%), positive predictive value (74.3%), and negative predictive value (75.0%). The ROC area under the curve (AUC) for this study was 0.82 (95% confidence interval: 0.70 to 0.90).Conclusion: The Thai version of the MDQ had some useful psychometric properties for screening for bipolar disorder in a mood disorder clinic setting, with a recommended question #1 item threshold value of at least five positive items. Keywords: Thai MDQ, screening test, reliability, predictive validity, cutoff pointWaleeprakhon PIttasakul PLotrakul MWisajun PJullagate SKetter TADove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2014, Iss default, Pp 1497-1502 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Waleeprakhon P Ittasakul P Lotrakul M Wisajun P Jullagate S Ketter TA Development and validation of a screening instrument for bipolar spectrum disorder: The Mood Disorder Questionnaire Thai version
description	Punjaporn Waleeprakhon,1 Pichai Ittasakul,1 Manote Lotrakul,1 Pattarabhorn Wisajun,1 Sudawan Jullagate,1 Terence A Ketter2 1Department of Psychiatry, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; 2Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA Background: The Mood Disorder Questionnaire (MDQ) has been translated to many languages and has been used in many countries as a screening instrument for bipolar disorder. The main objective of this study was to evaluate validity of the Thai version of the MDQ as a screening instrument for bipolar disorder in a psychiatric outpatient sample, and to determine its optimum question #1 item threshold value for bipolar disorder.Methods: The English language Mood Disorder Questionnaire (MDQ) was translated into Thai. The process involved back-translation, cross-cultural adaptation, field testing of the prefinal version, as well as final adjustments. Two hundred and fifty major depressive disorder outpatients were further assessed by the Thai version of the MDQ and the Thai version of the Mini International Neuropsychiatric Interview (MINI). During the assessment, reliability and validity analyses, and receiver operating characteristic curve (ROC) analysis were performed.Results: The Thai version of the MDQ screening had adequate internal consistency (Cronbach’s alpha =0.791, omega total =0.68, and omega hierarchical =0.69). The optimal question #1 item threshold value was at least five positive items, which yielded adequate sensitivity (76.5%), specificity (72.7%), positive predictive value (74.3%), and negative predictive value (75.0%). The ROC area under the curve (AUC) for this study was 0.82 (95% confidence interval: 0.70 to 0.90).Conclusion: The Thai version of the MDQ had some useful psychometric properties for screening for bipolar disorder in a mood disorder clinic setting, with a recommended question #1 item threshold value of at least five positive items. Keywords: Thai MDQ, screening test, reliability, predictive validity, cutoff point
format	article
author	Waleeprakhon P Ittasakul P Lotrakul M Wisajun P Jullagate S Ketter TA
author_facet	Waleeprakhon P Ittasakul P Lotrakul M Wisajun P Jullagate S Ketter TA
author_sort	Waleeprakhon P
title	Development and validation of a screening instrument for bipolar spectrum disorder: The Mood Disorder Questionnaire Thai version
title_short	Development and validation of a screening instrument for bipolar spectrum disorder: The Mood Disorder Questionnaire Thai version
title_full	Development and validation of a screening instrument for bipolar spectrum disorder: The Mood Disorder Questionnaire Thai version
title_fullStr	Development and validation of a screening instrument for bipolar spectrum disorder: The Mood Disorder Questionnaire Thai version
title_full_unstemmed	Development and validation of a screening instrument for bipolar spectrum disorder: The Mood Disorder Questionnaire Thai version
title_sort	development and validation of a screening instrument for bipolar spectrum disorder: the mood disorder questionnaire thai version
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/03cf749dc515434f827089341d388789
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Development and validation of a screening instrument for bipolar spectrum disorder: The Mood Disorder Questionnaire Thai version

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