Are suspensory ligaments important for middle ear reconstruction?

As the resolution of 3D printing techniques improves, the possibility of individualized, 3-ossicle constructions adds a new dimension to middle ear prostheses. In order to optimize these designs, it is essential to understand how the ossicles and ligaments work together to transmit sound, and thus h...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Eileen Y Brister, Robert H Withnell, Pavel Shevchenko, Claus-Peter Richter
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/03d173b11bd24391a03591b831185d82
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:03d173b11bd24391a03591b831185d82
record_format	dspace
spelling	oai:doaj.org-article:03d173b11bd24391a03591b831185d822021-12-02T20:17:38ZAre suspensory ligaments important for middle ear reconstruction?1932-620310.1371/journal.pone.0255821https://doaj.org/article/03d173b11bd24391a03591b831185d822021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0255821https://doaj.org/toc/1932-6203As the resolution of 3D printing techniques improves, the possibility of individualized, 3-ossicle constructions adds a new dimension to middle ear prostheses. In order to optimize these designs, it is essential to understand how the ossicles and ligaments work together to transmit sound, and thus how ligaments should be replicated in a middle ear reconstruction. The middle ear ligaments are thought to play a significant role in maintaining the position of the ossicles and constraining axis of rotation. Paradoxically, investigations of the role of ligaments to date have shown very little impact on middle ear sound transmission. We explored the role of the two attachments in the gerbil middle ear analogous to human ligaments, the posterior incudal ligament and the anterior mallear process, severing both attachments and measuring change in hearing sensitivity. The impact of severing the attachments on the position of the ossicular chain was visualized using synchrotron microtomography imaging of the middle ear. In contrast to previous studies, a threshold change on the order of 20 dB across a wide range of frequencies was found when both ligaments were severed. Concomitantly, a shift in position of the ossicles was observed from the x-ray imaging and 3D renderings of the ossicular chain. These findings contrast with previous studies, demonstrating that these ligaments play a significant role in the transmission of sound through the middle ear. It appears that both mallear and incudal ligaments must be severed in order to impair sound transmission. The results of this study have significance for middle ear reconstructive surgery and the design of 3D-printed three-ossicle biocompatible prostheses.Eileen Y BristerRobert H WithnellPavel ShevchenkoClaus-Peter RichterPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 8, p e0255821 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Eileen Y Brister Robert H Withnell Pavel Shevchenko Claus-Peter Richter Are suspensory ligaments important for middle ear reconstruction?
description	As the resolution of 3D printing techniques improves, the possibility of individualized, 3-ossicle constructions adds a new dimension to middle ear prostheses. In order to optimize these designs, it is essential to understand how the ossicles and ligaments work together to transmit sound, and thus how ligaments should be replicated in a middle ear reconstruction. The middle ear ligaments are thought to play a significant role in maintaining the position of the ossicles and constraining axis of rotation. Paradoxically, investigations of the role of ligaments to date have shown very little impact on middle ear sound transmission. We explored the role of the two attachments in the gerbil middle ear analogous to human ligaments, the posterior incudal ligament and the anterior mallear process, severing both attachments and measuring change in hearing sensitivity. The impact of severing the attachments on the position of the ossicular chain was visualized using synchrotron microtomography imaging of the middle ear. In contrast to previous studies, a threshold change on the order of 20 dB across a wide range of frequencies was found when both ligaments were severed. Concomitantly, a shift in position of the ossicles was observed from the x-ray imaging and 3D renderings of the ossicular chain. These findings contrast with previous studies, demonstrating that these ligaments play a significant role in the transmission of sound through the middle ear. It appears that both mallear and incudal ligaments must be severed in order to impair sound transmission. The results of this study have significance for middle ear reconstructive surgery and the design of 3D-printed three-ossicle biocompatible prostheses.
format	article
author	Eileen Y Brister Robert H Withnell Pavel Shevchenko Claus-Peter Richter
author_facet	Eileen Y Brister Robert H Withnell Pavel Shevchenko Claus-Peter Richter
author_sort	Eileen Y Brister
title	Are suspensory ligaments important for middle ear reconstruction?
title_short	Are suspensory ligaments important for middle ear reconstruction?
title_full	Are suspensory ligaments important for middle ear reconstruction?
title_fullStr	Are suspensory ligaments important for middle ear reconstruction?
title_full_unstemmed	Are suspensory ligaments important for middle ear reconstruction?
title_sort	are suspensory ligaments important for middle ear reconstruction?
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/03d173b11bd24391a03591b831185d82
work_keys_str_mv	AT eileenybrister aresuspensoryligamentsimportantformiddleearreconstruction AT roberthwithnell aresuspensoryligamentsimportantformiddleearreconstruction AT pavelshevchenko aresuspensoryligamentsimportantformiddleearreconstruction AT clauspeterrichter aresuspensoryligamentsimportantformiddleearreconstruction
_version_	1718374325977874432

Are suspensory ligaments important for middle ear reconstruction?

Ejemplares similares