The Effect of Administering Lemon Basil (Ocimum sanctum) Leaves on FSH and LH Estrogen Levels and Size of Ovarian Antral Follicle in Female Balb/C Mice

INTRODUCTION: Ocimum sanctum have been proven effective in decreasing Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH) levels, and sperm number, and also increase male testosterone levels. However, so far no evidence has been found on the effect of Ocimum sanctum leaves on the levels of...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Sri Maryanti, Taufiqurrachman Nasihun, Helfi Amalia
Formato:	article
Lenguaje:	EN
Publicado:	Universitas Sultan Agung Semarang 2020
Materias:	ocimum sanctum, estrogen, fsh, lh, ovary area Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/03dc2ed6a7574f2faa79b0516fbff1e0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:03dc2ed6a7574f2faa79b0516fbff1e0
record_format	dspace
spelling	oai:doaj.org-article:03dc2ed6a7574f2faa79b0516fbff1e02021-11-25T13:16:27ZThe Effect of Administering Lemon Basil (Ocimum sanctum) Leaves on FSH and LH Estrogen Levels and Size of Ovarian Antral Follicle in Female Balb/C Mice2085-15452339-093X10.30659/sainsmed.v10i2.2612https://doaj.org/article/03dc2ed6a7574f2faa79b0516fbff1e02020-03-01T00:00:00Zhttp://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/2612https://doaj.org/toc/2085-1545https://doaj.org/toc/2339-093XINTRODUCTION: Ocimum sanctum have been proven effective in decreasing Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH) levels, and sperm number, and also increase male testosterone levels. However, so far no evidence has been found on the effect of Ocimum sanctum leaves on the levels of estrogen, FSH, LH, and the size of ovarian anthral follicles. OBJECTIVES: To evaluate the effect of Ocimum sanctum leaves on estrogen, FSH, LH and the size of antral follicle of female Balb/C mice. METHODS: In the post test only control group design, 12 female Balb/C mice were assigned into 2 groups. The treatment group (OS-G) was given 0.08 gram of ocimum sanctum leaves, three times a day for 30 days and the control group (C-G) received no ocimum sanctum. Estrogen, FSH anduLH levels wereumeasured on the 30th day, the mice were sacrificed and taken up by their ovaries. HE preparationsuwere then madeuand HE was performed, and the size of the antral follicle of the ovary was measured . RESULTS: Mann Whitney analysisuindicateduthat estrogen and FSH levels in OS-G group were significantly higher compared to that of C-G group, p<0.05. Based on independent t-test, the level of LH in OS-G was significantly higher than that of C-Gugroup, p><0.05. On the contrary, uthe size of ovarianuanthralufollicle in OS-Guwas smaller than that of C-Gugroup, p><0.05. CONCLUSION: Ocimum sanctum increased the levels of estrogen, FSH, LH and decreased the size of ovarian antral follicle in female of Balb/C mice.>Sri MaryantiTaufiqurrachman NasihunHelfi AmaliaUniversitas Sultan Agung Semarangarticleocimum sanctum, estrogen, fsh, lh, ovary areaMedicine (General)R5-920ENSains Medika, Vol 10, Iss 2, Pp 57-61 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	ocimum sanctum, estrogen, fsh, lh, ovary area Medicine (General) R5-920
spellingShingle	ocimum sanctum, estrogen, fsh, lh, ovary area Medicine (General) R5-920 Sri Maryanti Taufiqurrachman Nasihun Helfi Amalia The Effect of Administering Lemon Basil (Ocimum sanctum) Leaves on FSH and LH Estrogen Levels and Size of Ovarian Antral Follicle in Female Balb/C Mice
description	INTRODUCTION: Ocimum sanctum have been proven effective in decreasing Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH) levels, and sperm number, and also increase male testosterone levels. However, so far no evidence has been found on the effect of Ocimum sanctum leaves on the levels of estrogen, FSH, LH, and the size of ovarian anthral follicles. OBJECTIVES: To evaluate the effect of Ocimum sanctum leaves on estrogen, FSH, LH and the size of antral follicle of female Balb/C mice. METHODS: In the post test only control group design, 12 female Balb/C mice were assigned into 2 groups. The treatment group (OS-G) was given 0.08 gram of ocimum sanctum leaves, three times a day for 30 days and the control group (C-G) received no ocimum sanctum. Estrogen, FSH anduLH levels wereumeasured on the 30th day, the mice were sacrificed and taken up by their ovaries. HE preparationsuwere then madeuand HE was performed, and the size of the antral follicle of the ovary was measured . RESULTS: Mann Whitney analysisuindicateduthat estrogen and FSH levels in OS-G group were significantly higher compared to that of C-G group, p<0.05. Based on independent t-test, the level of LH in OS-G was significantly higher than that of C-Gugroup, p><0.05. On the contrary, uthe size of ovarianuanthralufollicle in OS-Guwas smaller than that of C-Gugroup, p><0.05. CONCLUSION: Ocimum sanctum increased the levels of estrogen, FSH, LH and decreased the size of ovarian antral follicle in female of Balb/C mice.>
format	article
author	Sri Maryanti Taufiqurrachman Nasihun Helfi Amalia
author_facet	Sri Maryanti Taufiqurrachman Nasihun Helfi Amalia
author_sort	Sri Maryanti
title	The Effect of Administering Lemon Basil (Ocimum sanctum) Leaves on FSH and LH Estrogen Levels and Size of Ovarian Antral Follicle in Female Balb/C Mice
title_short	The Effect of Administering Lemon Basil (Ocimum sanctum) Leaves on FSH and LH Estrogen Levels and Size of Ovarian Antral Follicle in Female Balb/C Mice
title_full	The Effect of Administering Lemon Basil (Ocimum sanctum) Leaves on FSH and LH Estrogen Levels and Size of Ovarian Antral Follicle in Female Balb/C Mice
title_fullStr	The Effect of Administering Lemon Basil (Ocimum sanctum) Leaves on FSH and LH Estrogen Levels and Size of Ovarian Antral Follicle in Female Balb/C Mice
title_full_unstemmed	The Effect of Administering Lemon Basil (Ocimum sanctum) Leaves on FSH and LH Estrogen Levels and Size of Ovarian Antral Follicle in Female Balb/C Mice
title_sort	effect of administering lemon basil (ocimum sanctum) leaves on fsh and lh estrogen levels and size of ovarian antral follicle in female balb/c mice
publisher	Universitas Sultan Agung Semarang
publishDate	2020
url	https://doaj.org/article/03dc2ed6a7574f2faa79b0516fbff1e0
work_keys_str_mv	AT srimaryanti theeffectofadministeringlemonbasilocimumsanctumleavesonfshandlhestrogenlevelsandsizeofovarianantralfollicleinfemalebalbcmice AT taufiqurrachmannasihun theeffectofadministeringlemonbasilocimumsanctumleavesonfshandlhestrogenlevelsandsizeofovarianantralfollicleinfemalebalbcmice AT helfiamalia theeffectofadministeringlemonbasilocimumsanctumleavesonfshandlhestrogenlevelsandsizeofovarianantralfollicleinfemalebalbcmice AT srimaryanti effectofadministeringlemonbasilocimumsanctumleavesonfshandlhestrogenlevelsandsizeofovarianantralfollicleinfemalebalbcmice AT taufiqurrachmannasihun effectofadministeringlemonbasilocimumsanctumleavesonfshandlhestrogenlevelsandsizeofovarianantralfollicleinfemalebalbcmice AT helfiamalia effectofadministeringlemonbasilocimumsanctumleavesonfshandlhestrogenlevelsandsizeofovarianantralfollicleinfemalebalbcmice
_version_	1718413477951832064

The Effect of Administering Lemon Basil (Ocimum sanctum) Leaves on FSH and LH Estrogen Levels and Size of Ovarian Antral Follicle in Female Balb/C Mice

Ejemplares similares