Direct binding to GABARAP family members is essential for HIV-1 Nef plasma membrane localization

Direct binding to GABARAP family members is essential for HIV-1 Nef plasma membrane localization

Abstract HIV-1 Nef is an important pathogenic factor for HIV/AIDS pathogenesis. Studies have shown that the association of Nef with the inner leaflet of the plasma membrane and with endocytic and perinuclear vesicles is essential for most activities of Nef. Using purified recombinant proteins in pul...

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Autores principales: Alexandra Boeske, Melanie Schwarten, Peixiang Ma, Markus Tusche, Jessica Mötter, Christina Möller, Philipp Neudecker, Silke Hoffmann, Dieter Willbold
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/03e0e78ce7bf4b4b9c679247f861c77c
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