Differential gene expression in Drosophila melanogaster and D. nigrosparsa infected with the same Wolbachia strain

Abstract Wolbachia are maternally inherited endosymbionts that infect nearly half of all arthropod species. Wolbachia manipulate their hosts to maximize their transmission, but they can also provide benefits such as nutrients and resistance against viruses to their hosts. The Wolbachia strain wMel w...

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Autores principales:	Matsapume Detcharoen, Martin P. Schilling, Wolfgang Arthofer, Birgit C. Schlick-Steiner, Florian M. Steiner
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/03e3c99507724fbcb4ad4633dc0bdc76
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spelling	oai:doaj.org-article:03e3c99507724fbcb4ad4633dc0bdc762021-12-02T18:24:53ZDifferential gene expression in Drosophila melanogaster and D. nigrosparsa infected with the same Wolbachia strain10.1038/s41598-021-90857-52045-2322https://doaj.org/article/03e3c99507724fbcb4ad4633dc0bdc762021-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-90857-5https://doaj.org/toc/2045-2322Abstract Wolbachia are maternally inherited endosymbionts that infect nearly half of all arthropod species. Wolbachia manipulate their hosts to maximize their transmission, but they can also provide benefits such as nutrients and resistance against viruses to their hosts. The Wolbachia strain wMel was recently found to increase locomotor activities and possibly trigger cytoplasmic incompatibility in the transinfected fly Drosophila nigrosparsa. Here, we investigated, in females of both D. melanogaster and D. nigrosparsa, the gene expression between animals uninfected and infected with wMel, using RNA sequencing to see if the two Drosophila species respond to the infection in the same or different ways. A total of 2164 orthologous genes were used. The two fly species responded to the infection in different ways. Significant changes shared by the fly species belong to the expression of genes involved in processes such as oxidation–reduction process, iron-ion binding, and voltage-gated potassium-channel activity. We discuss our findings also in the light of how Wolbachia survive within both the native and the novel host.Matsapume DetcharoenMartin P. SchillingWolfgang ArthoferBirgit C. Schlick-SteinerFlorian M. SteinerNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Matsapume Detcharoen Martin P. Schilling Wolfgang Arthofer Birgit C. Schlick-Steiner Florian M. Steiner Differential gene expression in Drosophila melanogaster and D. nigrosparsa infected with the same Wolbachia strain
description	Abstract Wolbachia are maternally inherited endosymbionts that infect nearly half of all arthropod species. Wolbachia manipulate their hosts to maximize their transmission, but they can also provide benefits such as nutrients and resistance against viruses to their hosts. The Wolbachia strain wMel was recently found to increase locomotor activities and possibly trigger cytoplasmic incompatibility in the transinfected fly Drosophila nigrosparsa. Here, we investigated, in females of both D. melanogaster and D. nigrosparsa, the gene expression between animals uninfected and infected with wMel, using RNA sequencing to see if the two Drosophila species respond to the infection in the same or different ways. A total of 2164 orthologous genes were used. The two fly species responded to the infection in different ways. Significant changes shared by the fly species belong to the expression of genes involved in processes such as oxidation–reduction process, iron-ion binding, and voltage-gated potassium-channel activity. We discuss our findings also in the light of how Wolbachia survive within both the native and the novel host.
format	article
author	Matsapume Detcharoen Martin P. Schilling Wolfgang Arthofer Birgit C. Schlick-Steiner Florian M. Steiner
author_facet	Matsapume Detcharoen Martin P. Schilling Wolfgang Arthofer Birgit C. Schlick-Steiner Florian M. Steiner
author_sort	Matsapume Detcharoen
title	Differential gene expression in Drosophila melanogaster and D. nigrosparsa infected with the same Wolbachia strain
title_short	Differential gene expression in Drosophila melanogaster and D. nigrosparsa infected with the same Wolbachia strain
title_full	Differential gene expression in Drosophila melanogaster and D. nigrosparsa infected with the same Wolbachia strain
title_fullStr	Differential gene expression in Drosophila melanogaster and D. nigrosparsa infected with the same Wolbachia strain
title_full_unstemmed	Differential gene expression in Drosophila melanogaster and D. nigrosparsa infected with the same Wolbachia strain
title_sort	differential gene expression in drosophila melanogaster and d. nigrosparsa infected with the same wolbachia strain
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/03e3c99507724fbcb4ad4633dc0bdc76
work_keys_str_mv	AT matsapumedetcharoen differentialgeneexpressionindrosophilamelanogasteranddnigrosparsainfectedwiththesamewolbachiastrain AT martinpschilling differentialgeneexpressionindrosophilamelanogasteranddnigrosparsainfectedwiththesamewolbachiastrain AT wolfgangarthofer differentialgeneexpressionindrosophilamelanogasteranddnigrosparsainfectedwiththesamewolbachiastrain AT birgitcschlicksteiner differentialgeneexpressionindrosophilamelanogasteranddnigrosparsainfectedwiththesamewolbachiastrain AT florianmsteiner differentialgeneexpressionindrosophilamelanogasteranddnigrosparsainfectedwiththesamewolbachiastrain
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Differential gene expression in Drosophila melanogaster and D. nigrosparsa infected with the same Wolbachia strain

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