Carbon nanotubes and graphene as emerging candidates in neuroregeneration and neurodrug delivery

Agnes Aruna John,1 Aruna Priyadharshni Subramanian,1 Muthu Vignesh Vellayappan,1 Arunpandian Balaji,1 Hemanth Mohandas,2 Saravana Kumar Jaganathan1 1IJN-UTM Cardiovascular Engineering Centre, Faculty of Biosciences and Medical Engineering, Universiti Teknologi Malaysia, Johor Bahru, Malays...

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Autores principales:	John AA, Subramanian AP, Vellayappan MV, Balaji A, Mohandas H, Jaganathan SK
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/03e58ed646894e4f9e9bd9eb7540edb0
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spelling	oai:doaj.org-article:03e58ed646894e4f9e9bd9eb7540edb02021-12-02T00:46:38ZCarbon nanotubes and graphene as emerging candidates in neuroregeneration and neurodrug delivery1178-2013https://doaj.org/article/03e58ed646894e4f9e9bd9eb7540edb02015-07-01T00:00:00Zhttp://www.dovepress.com/carbon-nanotubes-and-graphene-as-emerging-candidates-in-neuroregenerat-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Agnes Aruna John,1 Aruna Priyadharshni Subramanian,1 Muthu Vignesh Vellayappan,1 Arunpandian Balaji,1 Hemanth Mohandas,2 Saravana Kumar Jaganathan1 1IJN-UTM Cardiovascular Engineering Centre, Faculty of Biosciences and Medical Engineering, Universiti Teknologi Malaysia, Johor Bahru, Malaysia; 2Department of Biomedical Engineering, University of Texas at Arlington, Arlington, TX, USA Abstract: Neuroregeneration is the regrowth or repair of nervous tissues, cells, or cell products involved in neurodegeneration and inflammatory diseases of the nervous system like Alzheimer’s disease and Parkinson’s disease. Nowadays, application of nanotechnology is commonly used in developing nanomedicines to advance pharmacokinetics and drug delivery exclusively for central nervous system pathologies. In addition, nanomedical advances are leading to therapies that disrupt disarranged protein aggregation in the central nervous system, deliver functional neuroprotective growth factors, and change the oxidative stress and excitotoxicity of affected neural tissues to regenerate the damaged neurons. Carbon nanotubes and graphene are allotropes of carbon that have been exploited by researchers because of their excellent physical properties and their ability to interface with neurons and neuronal circuits. This review describes the role of carbon nanotubes and graphene in neuroregeneration. In the future, it is hoped that the benefits of nanotechnologies will outweigh their risks, and that the next decade will present huge scope for developing and delivering technologies in the field of neuroscience. Keywords: neuroregeneration, neurodegeneration, nanomedical, carbon nanotube, graphene, nanodrug deliveryJohn AASubramanian APVellayappan MVBalaji AMohandas HJaganathan SKDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2015, Iss default, Pp 4267-4277 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 John AA Subramanian AP Vellayappan MV Balaji A Mohandas H Jaganathan SK Carbon nanotubes and graphene as emerging candidates in neuroregeneration and neurodrug delivery
description	Agnes Aruna John,1 Aruna Priyadharshni Subramanian,1 Muthu Vignesh Vellayappan,1 Arunpandian Balaji,1 Hemanth Mohandas,2 Saravana Kumar Jaganathan1 1IJN-UTM Cardiovascular Engineering Centre, Faculty of Biosciences and Medical Engineering, Universiti Teknologi Malaysia, Johor Bahru, Malaysia; 2Department of Biomedical Engineering, University of Texas at Arlington, Arlington, TX, USA Abstract: Neuroregeneration is the regrowth or repair of nervous tissues, cells, or cell products involved in neurodegeneration and inflammatory diseases of the nervous system like Alzheimer’s disease and Parkinson’s disease. Nowadays, application of nanotechnology is commonly used in developing nanomedicines to advance pharmacokinetics and drug delivery exclusively for central nervous system pathologies. In addition, nanomedical advances are leading to therapies that disrupt disarranged protein aggregation in the central nervous system, deliver functional neuroprotective growth factors, and change the oxidative stress and excitotoxicity of affected neural tissues to regenerate the damaged neurons. Carbon nanotubes and graphene are allotropes of carbon that have been exploited by researchers because of their excellent physical properties and their ability to interface with neurons and neuronal circuits. This review describes the role of carbon nanotubes and graphene in neuroregeneration. In the future, it is hoped that the benefits of nanotechnologies will outweigh their risks, and that the next decade will present huge scope for developing and delivering technologies in the field of neuroscience. Keywords: neuroregeneration, neurodegeneration, nanomedical, carbon nanotube, graphene, nanodrug delivery
format	article
author	John AA Subramanian AP Vellayappan MV Balaji A Mohandas H Jaganathan SK
author_facet	John AA Subramanian AP Vellayappan MV Balaji A Mohandas H Jaganathan SK
author_sort	John AA
title	Carbon nanotubes and graphene as emerging candidates in neuroregeneration and neurodrug delivery
title_short	Carbon nanotubes and graphene as emerging candidates in neuroregeneration and neurodrug delivery
title_full	Carbon nanotubes and graphene as emerging candidates in neuroregeneration and neurodrug delivery
title_fullStr	Carbon nanotubes and graphene as emerging candidates in neuroregeneration and neurodrug delivery
title_full_unstemmed	Carbon nanotubes and graphene as emerging candidates in neuroregeneration and neurodrug delivery
title_sort	carbon nanotubes and graphene as emerging candidates in neuroregeneration and neurodrug delivery
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/03e58ed646894e4f9e9bd9eb7540edb0
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Carbon nanotubes and graphene as emerging candidates in neuroregeneration and neurodrug delivery

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