Activity dependent protein degradation is critical for the formation and stability of fear memory in the amygdala.

Protein degradation through the ubiquitin-proteasome system [UPS] plays a critical role in some forms of synaptic plasticity. However, its role in memory formation in the amygdala, a site critical for the formation of fear memories, currently remains unknown. Here we provide the first evidence that...

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Auteurs principaux: Timothy J Jarome, Craig T Werner, Janine L Kwapis, Fred J Helmstetter
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
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Accès en ligne:https://doaj.org/article/03e78f20d63946e699dc6037aa7c59d5
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