Nasobiliary Drain Diverted through a Percutaneous Endoscopic Gastrostomy Tube: A Novel Approach to Nasobiliary Drainage

Intractable pruritus is a common, debilitating symptom and a well-defined entity occurring in chronic cholestatic disorders. Treatment options include cholestyramine, rifampicin, naltrexone, gabapentin, and sertraline, as well as more interventional measures, such as plasmapheresis, extracorporeal a...

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Autores principales: Nikolaos Dimitrios Pantzaris, Tim Lord, Robyn Sotheran, John Hutchinson, Charles Millson
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Lenguaje:EN
Publicado: Karger Publishers 2021
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Acceso en línea:https://doaj.org/article/03e79515180e45e9bc172d02e5afb026
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spelling oai:doaj.org-article:03e79515180e45e9bc172d02e5afb0262021-11-04T14:40:31ZNasobiliary Drain Diverted through a Percutaneous Endoscopic Gastrostomy Tube: A Novel Approach to Nasobiliary Drainage1662-063110.1159/000518057https://doaj.org/article/03e79515180e45e9bc172d02e5afb0262021-10-01T00:00:00Zhttps://www.karger.com/Article/FullText/518057https://doaj.org/toc/1662-0631Intractable pruritus is a common, debilitating symptom and a well-defined entity occurring in chronic cholestatic disorders. Treatment options include cholestyramine, rifampicin, naltrexone, gabapentin, and sertraline, as well as more interventional measures, such as plasmapheresis, extracorporeal albumin dialysis, nasobiliary drains (NBDs), and UVB phototherapy in patients who fail to respond to medical therapy. Despite the limited data, NBD seems to be a highly effective treatment in the relief of refractory cholestatic pruritus. In this article, we present the case of a 73-year-old woman with primary biliary cholangitis and intractable pruritus, refractory to medical treatment. The patient had a complete resolution of her symptoms following an NBD placement, in which, with a novel approach, the nasal end was redirected and exited through a percutaneous endoscopic gastrostomy port, significantly improving her quality of life.Nikolaos Dimitrios PantzarisTim LordRobyn SotheranJohn HutchinsonCharles MillsonKarger Publishersarticleprimary biliary cholangitispruritusnasobiliary drainbiliary drainpercutaneous endoscopic gastrostomyDiseases of the digestive system. GastroenterologyRC799-869ENCase Reports in Gastroenterology, Vol 15, Iss 3, Pp 891-897 (2021)
institution DOAJ
collection DOAJ
language EN
topic primary biliary cholangitis
pruritus
nasobiliary drain
biliary drain
percutaneous endoscopic gastrostomy
Diseases of the digestive system. Gastroenterology
RC799-869
spellingShingle primary biliary cholangitis
pruritus
nasobiliary drain
biliary drain
percutaneous endoscopic gastrostomy
Diseases of the digestive system. Gastroenterology
RC799-869
Nikolaos Dimitrios Pantzaris
Tim Lord
Robyn Sotheran
John Hutchinson
Charles Millson
Nasobiliary Drain Diverted through a Percutaneous Endoscopic Gastrostomy Tube: A Novel Approach to Nasobiliary Drainage
description Intractable pruritus is a common, debilitating symptom and a well-defined entity occurring in chronic cholestatic disorders. Treatment options include cholestyramine, rifampicin, naltrexone, gabapentin, and sertraline, as well as more interventional measures, such as plasmapheresis, extracorporeal albumin dialysis, nasobiliary drains (NBDs), and UVB phototherapy in patients who fail to respond to medical therapy. Despite the limited data, NBD seems to be a highly effective treatment in the relief of refractory cholestatic pruritus. In this article, we present the case of a 73-year-old woman with primary biliary cholangitis and intractable pruritus, refractory to medical treatment. The patient had a complete resolution of her symptoms following an NBD placement, in which, with a novel approach, the nasal end was redirected and exited through a percutaneous endoscopic gastrostomy port, significantly improving her quality of life.
format article
author Nikolaos Dimitrios Pantzaris
Tim Lord
Robyn Sotheran
John Hutchinson
Charles Millson
author_facet Nikolaos Dimitrios Pantzaris
Tim Lord
Robyn Sotheran
John Hutchinson
Charles Millson
author_sort Nikolaos Dimitrios Pantzaris
title Nasobiliary Drain Diverted through a Percutaneous Endoscopic Gastrostomy Tube: A Novel Approach to Nasobiliary Drainage
title_short Nasobiliary Drain Diverted through a Percutaneous Endoscopic Gastrostomy Tube: A Novel Approach to Nasobiliary Drainage
title_full Nasobiliary Drain Diverted through a Percutaneous Endoscopic Gastrostomy Tube: A Novel Approach to Nasobiliary Drainage
title_fullStr Nasobiliary Drain Diverted through a Percutaneous Endoscopic Gastrostomy Tube: A Novel Approach to Nasobiliary Drainage
title_full_unstemmed Nasobiliary Drain Diverted through a Percutaneous Endoscopic Gastrostomy Tube: A Novel Approach to Nasobiliary Drainage
title_sort nasobiliary drain diverted through a percutaneous endoscopic gastrostomy tube: a novel approach to nasobiliary drainage
publisher Karger Publishers
publishDate 2021
url https://doaj.org/article/03e79515180e45e9bc172d02e5afb026
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AT timlord nasobiliarydraindivertedthroughapercutaneousendoscopicgastrostomytubeanovelapproachtonasobiliarydrainage
AT robynsotheran nasobiliarydraindivertedthroughapercutaneousendoscopicgastrostomytubeanovelapproachtonasobiliarydrainage
AT johnhutchinson nasobiliarydraindivertedthroughapercutaneousendoscopicgastrostomytubeanovelapproachtonasobiliarydrainage
AT charlesmillson nasobiliarydraindivertedthroughapercutaneousendoscopicgastrostomytubeanovelapproachtonasobiliarydrainage
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