A whole-body model for glycogen regulation reveals a critical role for substrate cycling in maintaining blood glucose homeostasis.

Timely, and sometimes rapid, metabolic adaptation to changes in food supply is critical for survival as an organism moves from the fasted to the fed state, and vice versa. These transitions necessitate major metabolic changes to maintain energy homeostasis as the source of blood glucose moves away f...

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Bibliographic Details
Main Authors: Ke Xu, Kevin T Morgan, Abby Todd Gehris, Timothy C Elston, Shawn M Gomez
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
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Online Access:https://doaj.org/article/03f02b4cbced4e46ada869f29d364880
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