TROPHOBLASTIC β1 – GLYCOPROTEIN SYNTHESIS IN SEROPOSITIVE PREGNANT WOMEN

Abstract. The level of trophoblastic β1 – glycoprotein (SP–1) was determined in the blood sera of 200 healthy pregnant women and 184 women with threatened abortions in term till 20 weeks of pregnancy. In group of women experiencing recurrent abortions in 38 % cases antibodies to chorionic gonadotrop...

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Autores principales: R. N. Bogdanovich, I. V. Tchikalovetz, N. N. Bandur
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Lenguaje:RU
Publicado: SPb RAACI 2014
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Acceso en línea:https://doaj.org/article/03f1342fcb9f463192131af4eb4cbfed
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spelling oai:doaj.org-article:03f1342fcb9f463192131af4eb4cbfed2021-11-18T08:03:41ZTROPHOBLASTIC β1 – GLYCOPROTEIN SYNTHESIS IN SEROPOSITIVE PREGNANT WOMEN1563-06252313-741X10.15789/1563-0625-2005-1-85-88https://doaj.org/article/03f1342fcb9f463192131af4eb4cbfed2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/438https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. The level of trophoblastic β1 – glycoprotein (SP–1) was determined in the blood sera of 200 healthy pregnant women and 184 women with threatened abortions in term till 20 weeks of pregnancy. In group of women experiencing recurrent abortions in 38 % cases antibodies to chorionic gonadotropin, in 39,5 % cases antibodies to phospholipids, in 25,5 % – antibodies to tireoglobulin were revealed in significant amounts. In 20,65 % lupus anticoagulant was found. The majority of women in this group had changes in homeostasis. The presence of autoantibodies during pregnancy is the unfavourable factor in the development of placental insufficiency. This is proved by the decreased secretion of trophoblastic β1 – glycoprotein – a marker of the fetal part of placenta. (Med. Immunol., 2005, vol.7, № 1, pp. 85588)R. N. BogdanovichI. V. TchikalovetzN. N. BandurSPb RAACIarticleautoimmune disorderstrophoblastic β1-glycoproteinhomeostasisImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 7, Iss 1, Pp 85-88 (2014)
institution DOAJ
collection DOAJ
language RU
topic autoimmune disorders
trophoblastic β1-glycoprotein
homeostasis
Immunologic diseases. Allergy
RC581-607
spellingShingle autoimmune disorders
trophoblastic β1-glycoprotein
homeostasis
Immunologic diseases. Allergy
RC581-607
R. N. Bogdanovich
I. V. Tchikalovetz
N. N. Bandur
TROPHOBLASTIC β1 – GLYCOPROTEIN SYNTHESIS IN SEROPOSITIVE PREGNANT WOMEN
description Abstract. The level of trophoblastic β1 – glycoprotein (SP–1) was determined in the blood sera of 200 healthy pregnant women and 184 women with threatened abortions in term till 20 weeks of pregnancy. In group of women experiencing recurrent abortions in 38 % cases antibodies to chorionic gonadotropin, in 39,5 % cases antibodies to phospholipids, in 25,5 % – antibodies to tireoglobulin were revealed in significant amounts. In 20,65 % lupus anticoagulant was found. The majority of women in this group had changes in homeostasis. The presence of autoantibodies during pregnancy is the unfavourable factor in the development of placental insufficiency. This is proved by the decreased secretion of trophoblastic β1 – glycoprotein – a marker of the fetal part of placenta. (Med. Immunol., 2005, vol.7, № 1, pp. 85588)
format article
author R. N. Bogdanovich
I. V. Tchikalovetz
N. N. Bandur
author_facet R. N. Bogdanovich
I. V. Tchikalovetz
N. N. Bandur
author_sort R. N. Bogdanovich
title TROPHOBLASTIC β1 – GLYCOPROTEIN SYNTHESIS IN SEROPOSITIVE PREGNANT WOMEN
title_short TROPHOBLASTIC β1 – GLYCOPROTEIN SYNTHESIS IN SEROPOSITIVE PREGNANT WOMEN
title_full TROPHOBLASTIC β1 – GLYCOPROTEIN SYNTHESIS IN SEROPOSITIVE PREGNANT WOMEN
title_fullStr TROPHOBLASTIC β1 – GLYCOPROTEIN SYNTHESIS IN SEROPOSITIVE PREGNANT WOMEN
title_full_unstemmed TROPHOBLASTIC β1 – GLYCOPROTEIN SYNTHESIS IN SEROPOSITIVE PREGNANT WOMEN
title_sort trophoblastic β1 – glycoprotein synthesis in seropositive pregnant women
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/03f1342fcb9f463192131af4eb4cbfed
work_keys_str_mv AT rnbogdanovich trophoblasticb1glycoproteinsynthesisinseropositivepregnantwomen
AT ivtchikalovetz trophoblasticb1glycoproteinsynthesisinseropositivepregnantwomen
AT nnbandur trophoblasticb1glycoproteinsynthesisinseropositivepregnantwomen
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