TROPHOBLASTIC β1 – GLYCOPROTEIN SYNTHESIS IN SEROPOSITIVE PREGNANT WOMEN
Abstract. The level of trophoblastic β1 – glycoprotein (SP–1) was determined in the blood sera of 200 healthy pregnant women and 184 women with threatened abortions in term till 20 weeks of pregnancy. In group of women experiencing recurrent abortions in 38 % cases antibodies to chorionic gonadotrop...
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SPb RAACI
2014
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oai:doaj.org-article:03f1342fcb9f463192131af4eb4cbfed2021-11-18T08:03:41ZTROPHOBLASTIC β1 – GLYCOPROTEIN SYNTHESIS IN SEROPOSITIVE PREGNANT WOMEN1563-06252313-741X10.15789/1563-0625-2005-1-85-88https://doaj.org/article/03f1342fcb9f463192131af4eb4cbfed2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/438https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. The level of trophoblastic β1 – glycoprotein (SP–1) was determined in the blood sera of 200 healthy pregnant women and 184 women with threatened abortions in term till 20 weeks of pregnancy. In group of women experiencing recurrent abortions in 38 % cases antibodies to chorionic gonadotropin, in 39,5 % cases antibodies to phospholipids, in 25,5 % – antibodies to tireoglobulin were revealed in significant amounts. In 20,65 % lupus anticoagulant was found. The majority of women in this group had changes in homeostasis. The presence of autoantibodies during pregnancy is the unfavourable factor in the development of placental insufficiency. This is proved by the decreased secretion of trophoblastic β1 – glycoprotein – a marker of the fetal part of placenta. (Med. Immunol., 2005, vol.7, № 1, pp. 85588)R. N. BogdanovichI. V. TchikalovetzN. N. BandurSPb RAACIarticleautoimmune disorderstrophoblastic β1-glycoproteinhomeostasisImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 7, Iss 1, Pp 85-88 (2014) |
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autoimmune disorders trophoblastic β1-glycoprotein homeostasis Immunologic diseases. Allergy RC581-607 |
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autoimmune disorders trophoblastic β1-glycoprotein homeostasis Immunologic diseases. Allergy RC581-607 R. N. Bogdanovich I. V. Tchikalovetz N. N. Bandur TROPHOBLASTIC β1 – GLYCOPROTEIN SYNTHESIS IN SEROPOSITIVE PREGNANT WOMEN |
description |
Abstract. The level of trophoblastic β1 – glycoprotein (SP–1) was determined in the blood sera of 200 healthy pregnant women and 184 women with threatened abortions in term till 20 weeks of pregnancy. In group of women experiencing recurrent abortions in 38 % cases antibodies to chorionic gonadotropin, in 39,5 % cases antibodies to phospholipids, in 25,5 % – antibodies to tireoglobulin were revealed in significant amounts. In 20,65 % lupus anticoagulant was found. The majority of women in this group had changes in homeostasis. The presence of autoantibodies during pregnancy is the unfavourable factor in the development of placental insufficiency. This is proved by the decreased secretion of trophoblastic β1 – glycoprotein – a marker of the fetal part of placenta. (Med. Immunol., 2005, vol.7, № 1, pp. 85588) |
format |
article |
author |
R. N. Bogdanovich I. V. Tchikalovetz N. N. Bandur |
author_facet |
R. N. Bogdanovich I. V. Tchikalovetz N. N. Bandur |
author_sort |
R. N. Bogdanovich |
title |
TROPHOBLASTIC β1 – GLYCOPROTEIN SYNTHESIS IN SEROPOSITIVE PREGNANT WOMEN |
title_short |
TROPHOBLASTIC β1 – GLYCOPROTEIN SYNTHESIS IN SEROPOSITIVE PREGNANT WOMEN |
title_full |
TROPHOBLASTIC β1 – GLYCOPROTEIN SYNTHESIS IN SEROPOSITIVE PREGNANT WOMEN |
title_fullStr |
TROPHOBLASTIC β1 – GLYCOPROTEIN SYNTHESIS IN SEROPOSITIVE PREGNANT WOMEN |
title_full_unstemmed |
TROPHOBLASTIC β1 – GLYCOPROTEIN SYNTHESIS IN SEROPOSITIVE PREGNANT WOMEN |
title_sort |
trophoblastic β1 – glycoprotein synthesis in seropositive pregnant women |
publisher |
SPb RAACI |
publishDate |
2014 |
url |
https://doaj.org/article/03f1342fcb9f463192131af4eb4cbfed |
work_keys_str_mv |
AT rnbogdanovich trophoblasticb1glycoproteinsynthesisinseropositivepregnantwomen AT ivtchikalovetz trophoblasticb1glycoproteinsynthesisinseropositivepregnantwomen AT nnbandur trophoblasticb1glycoproteinsynthesisinseropositivepregnantwomen |
_version_ |
1718422459786461184 |