Dutch population structure across space, time and GWAS design

Genetic variation in modern humans can reveal information about a population’s history and migration patterns. Here, the authors describe the ancestry and geospatial genetic structure of the Netherlands, and demonstrate the utility of haplotype-based covariates in genome-wide association studies.

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Detalles Bibliográficos
Autores principales:	Ross P. Byrne, Wouter van Rheenen, Project MinE ALS GWAS Consortium, Leonard H. van den Berg, Jan H. Veldink, Russell L. McLaughlin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/03f3a68c977f4d85996f5fe59dbf86ba
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spelling	oai:doaj.org-article:03f3a68c977f4d85996f5fe59dbf86ba2021-12-02T14:55:09ZDutch population structure across space, time and GWAS design10.1038/s41467-020-18418-42041-1723https://doaj.org/article/03f3a68c977f4d85996f5fe59dbf86ba2020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18418-4https://doaj.org/toc/2041-1723Genetic variation in modern humans can reveal information about a population’s history and migration patterns. Here, the authors describe the ancestry and geospatial genetic structure of the Netherlands, and demonstrate the utility of haplotype-based covariates in genome-wide association studies.Ross P. ByrneWouter van RheenenProject MinE ALS GWAS ConsortiumLeonard H. van den BergJan H. VeldinkRussell L. McLaughlinNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ross P. Byrne Wouter van Rheenen Project MinE ALS GWAS Consortium Leonard H. van den Berg Jan H. Veldink Russell L. McLaughlin Dutch population structure across space, time and GWAS design
description	Genetic variation in modern humans can reveal information about a population’s history and migration patterns. Here, the authors describe the ancestry and geospatial genetic structure of the Netherlands, and demonstrate the utility of haplotype-based covariates in genome-wide association studies.
format	article
author	Ross P. Byrne Wouter van Rheenen Project MinE ALS GWAS Consortium Leonard H. van den Berg Jan H. Veldink Russell L. McLaughlin
author_facet	Ross P. Byrne Wouter van Rheenen Project MinE ALS GWAS Consortium Leonard H. van den Berg Jan H. Veldink Russell L. McLaughlin
author_sort	Ross P. Byrne
title	Dutch population structure across space, time and GWAS design
title_short	Dutch population structure across space, time and GWAS design
title_full	Dutch population structure across space, time and GWAS design
title_fullStr	Dutch population structure across space, time and GWAS design
title_full_unstemmed	Dutch population structure across space, time and GWAS design
title_sort	dutch population structure across space, time and gwas design
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/03f3a68c977f4d85996f5fe59dbf86ba
work_keys_str_mv	AT rosspbyrne dutchpopulationstructureacrossspacetimeandgwasdesign AT woutervanrheenen dutchpopulationstructureacrossspacetimeandgwasdesign AT projectminealsgwasconsortium dutchpopulationstructureacrossspacetimeandgwasdesign AT leonardhvandenberg dutchpopulationstructureacrossspacetimeandgwasdesign AT janhveldink dutchpopulationstructureacrossspacetimeandgwasdesign AT russelllmclaughlin dutchpopulationstructureacrossspacetimeandgwasdesign
_version_	1718389303777689600

Dutch population structure across space, time and GWAS design

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