A transcribed enhancer dictates mesendoderm specification in pluripotency
Long noncoding RNAs (lncRNAs) are key regulators of lineage specification during development. Here, the authors investigate remodeling of enhancers and regulation of the lncRNA transcriptome during mesendoderm specification, and identify a pluripotent stage-specific transcribed enhancer controlling...
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Auteurs principaux: | Michael Alexanian, Daniel Maric, Stephen P. Jenkinson, Marco Mina, Clayton E. Friedman, Ching-Chia Ting, Rudi Micheletti, Isabelle Plaisance, Mohamed Nemir, Damien Maison, Jasmin Kernen, Iole Pezzuto, Dominic Villeneuve, Frédéric Burdet, Mark Ibberson, Stephen L. Leib, Nathan J. Palpant, Nouria Hernandez, Samir Ounzain, Thierry Pedrazzini |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
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Accès en ligne: | https://doaj.org/article/0401f32188554c209d1d26fb94e3d2e8 |
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