Multi-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors
Combining decellularised scaffolds with patient-derived cells holds promise for bioengineering of functional tissues. Here the authors develop a two-stage approach to engineer an oesophageal graft that retains the structural organisation of native oesophagus.
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Nature Portfolio
2018
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oai:doaj.org-article:04035db7e1a6472b9d4fc0a2bd25b51a2021-12-02T17:32:30ZMulti-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors10.1038/s41467-018-06385-w2041-1723https://doaj.org/article/04035db7e1a6472b9d4fc0a2bd25b51a2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06385-whttps://doaj.org/toc/2041-1723Combining decellularised scaffolds with patient-derived cells holds promise for bioengineering of functional tissues. Here the authors develop a two-stage approach to engineer an oesophageal graft that retains the structural organisation of native oesophagus.Luca UrbaniCarlotta CamilliDemetra-Ellie PhylactopoulosClaire CrowleyDipa NatarajanFederico ScottoniPanayiotis MaghsoudlouConor J. McCannAlessandro Filippo PellegataAnna UrciuoloKoichi DeguchiSahira KhalafSalvatore Ferdinando ArutaMaria Cristina SignorelliDavid KielyEdward HannonMatteo TrevisanRui Rachel WongMarc Olivier BaradezDale MouldingAlex VirasamiAsllan GjinovciStavros LoukogeorgakisSara ManteroNikhil ThaparNeil SebireSimon EatonMark LowdellGiulio CossuPaola BonfantiPaolo De CoppiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018) |
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DOAJ |
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DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Luca Urbani Carlotta Camilli Demetra-Ellie Phylactopoulos Claire Crowley Dipa Natarajan Federico Scottoni Panayiotis Maghsoudlou Conor J. McCann Alessandro Filippo Pellegata Anna Urciuolo Koichi Deguchi Sahira Khalaf Salvatore Ferdinando Aruta Maria Cristina Signorelli David Kiely Edward Hannon Matteo Trevisan Rui Rachel Wong Marc Olivier Baradez Dale Moulding Alex Virasami Asllan Gjinovci Stavros Loukogeorgakis Sara Mantero Nikhil Thapar Neil Sebire Simon Eaton Mark Lowdell Giulio Cossu Paola Bonfanti Paolo De Coppi Multi-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors |
| description |
Combining decellularised scaffolds with patient-derived cells holds promise for bioengineering of functional tissues. Here the authors develop a two-stage approach to engineer an oesophageal graft that retains the structural organisation of native oesophagus. |
| format |
article |
| author |
Luca Urbani Carlotta Camilli Demetra-Ellie Phylactopoulos Claire Crowley Dipa Natarajan Federico Scottoni Panayiotis Maghsoudlou Conor J. McCann Alessandro Filippo Pellegata Anna Urciuolo Koichi Deguchi Sahira Khalaf Salvatore Ferdinando Aruta Maria Cristina Signorelli David Kiely Edward Hannon Matteo Trevisan Rui Rachel Wong Marc Olivier Baradez Dale Moulding Alex Virasami Asllan Gjinovci Stavros Loukogeorgakis Sara Mantero Nikhil Thapar Neil Sebire Simon Eaton Mark Lowdell Giulio Cossu Paola Bonfanti Paolo De Coppi |
| author_facet |
Luca Urbani Carlotta Camilli Demetra-Ellie Phylactopoulos Claire Crowley Dipa Natarajan Federico Scottoni Panayiotis Maghsoudlou Conor J. McCann Alessandro Filippo Pellegata Anna Urciuolo Koichi Deguchi Sahira Khalaf Salvatore Ferdinando Aruta Maria Cristina Signorelli David Kiely Edward Hannon Matteo Trevisan Rui Rachel Wong Marc Olivier Baradez Dale Moulding Alex Virasami Asllan Gjinovci Stavros Loukogeorgakis Sara Mantero Nikhil Thapar Neil Sebire Simon Eaton Mark Lowdell Giulio Cossu Paola Bonfanti Paolo De Coppi |
| author_sort |
Luca Urbani |
| title |
Multi-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors |
| title_short |
Multi-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors |
| title_full |
Multi-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors |
| title_fullStr |
Multi-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors |
| title_full_unstemmed |
Multi-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors |
| title_sort |
multi-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/04035db7e1a6472b9d4fc0a2bd25b51a |
| work_keys_str_mv |
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