MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C
Chronic Hepatitis C infection is associated with a broad spectrum of liver pathologies, ranging from inflammation to fibrosis and liver cancer. Here Thabet et al. identified a polymorphism in the gene MBOAT7 that is associated with increased hepatic inflammation and higher risk of fibrosis developme...
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Nature Portfolio
2016
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oai:doaj.org-article:040377325d9345739aef54ce9c9e39f42021-12-02T17:32:52ZMBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C10.1038/ncomms127572041-1723https://doaj.org/article/040377325d9345739aef54ce9c9e39f42016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12757https://doaj.org/toc/2041-1723Chronic Hepatitis C infection is associated with a broad spectrum of liver pathologies, ranging from inflammation to fibrosis and liver cancer. Here Thabet et al. identified a polymorphism in the gene MBOAT7 that is associated with increased hepatic inflammation and higher risk of fibrosis development and progression.Khaled ThabetAnastasia AsimakopoulosMaryam ShojaeiManuel Romero-GomezAlessandra MangiaWilliam L. IrvingThomas BergGregory J. DoreHenning GrønbækDavid SheridanMaria Lorena AbateElisabetta BugianesiMartin WeltmanLindsay MollisonWendy ChengStephen RiordanJanett FischerUlrich SpenglerJacob NattermannAhmed WahidAngela RojasRose WhiteMark W. DouglasDuncan McLeodElizabeth PowellChristopher LiddleDavid van der PoortenJacob GeorgeMohammed EslamInternational Liver Disease Genetics ConsortiumNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016) |
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EN |
| topic |
Science Q |
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Science Q Khaled Thabet Anastasia Asimakopoulos Maryam Shojaei Manuel Romero-Gomez Alessandra Mangia William L. Irving Thomas Berg Gregory J. Dore Henning Grønbæk David Sheridan Maria Lorena Abate Elisabetta Bugianesi Martin Weltman Lindsay Mollison Wendy Cheng Stephen Riordan Janett Fischer Ulrich Spengler Jacob Nattermann Ahmed Wahid Angela Rojas Rose White Mark W. Douglas Duncan McLeod Elizabeth Powell Christopher Liddle David van der Poorten Jacob George Mohammed Eslam International Liver Disease Genetics Consortium MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C |
| description |
Chronic Hepatitis C infection is associated with a broad spectrum of liver pathologies, ranging from inflammation to fibrosis and liver cancer. Here Thabet et al. identified a polymorphism in the gene MBOAT7 that is associated with increased hepatic inflammation and higher risk of fibrosis development and progression. |
| format |
article |
| author |
Khaled Thabet Anastasia Asimakopoulos Maryam Shojaei Manuel Romero-Gomez Alessandra Mangia William L. Irving Thomas Berg Gregory J. Dore Henning Grønbæk David Sheridan Maria Lorena Abate Elisabetta Bugianesi Martin Weltman Lindsay Mollison Wendy Cheng Stephen Riordan Janett Fischer Ulrich Spengler Jacob Nattermann Ahmed Wahid Angela Rojas Rose White Mark W. Douglas Duncan McLeod Elizabeth Powell Christopher Liddle David van der Poorten Jacob George Mohammed Eslam International Liver Disease Genetics Consortium |
| author_facet |
Khaled Thabet Anastasia Asimakopoulos Maryam Shojaei Manuel Romero-Gomez Alessandra Mangia William L. Irving Thomas Berg Gregory J. Dore Henning Grønbæk David Sheridan Maria Lorena Abate Elisabetta Bugianesi Martin Weltman Lindsay Mollison Wendy Cheng Stephen Riordan Janett Fischer Ulrich Spengler Jacob Nattermann Ahmed Wahid Angela Rojas Rose White Mark W. Douglas Duncan McLeod Elizabeth Powell Christopher Liddle David van der Poorten Jacob George Mohammed Eslam International Liver Disease Genetics Consortium |
| author_sort |
Khaled Thabet |
| title |
MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C |
| title_short |
MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C |
| title_full |
MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C |
| title_fullStr |
MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C |
| title_full_unstemmed |
MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C |
| title_sort |
mboat7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis c |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/040377325d9345739aef54ce9c9e39f4 |
| work_keys_str_mv |
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