Electrochemical C–H phosphorylation of arenes in continuous flow suitable for late-stage functionalization

Synthesis of aryl phosphorus compounds with electron-withdrawing substituents on the arene is difficult to do simply. Here the authors show a method to form aryl carbon-phosphorus bonds through electrochemistry, without requiring any catalyst or external oxidant.

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Autores principales: Hao Long, Chong Huang, Yun-Tao Zheng, Zhao-Yu Li, Liang-Hua Jie, Jinshuai Song, Shaobin Zhu, Hai-Chao Xu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/040c115128194231a97296b5b1a1ae00
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