Precise inhibitory microcircuit assembly of developmentally related neocortical interneurons in clusters

Developmental neuroscientists have long asked if clonally-related neurons retain functional relationships after maturation. The authors show that sparsely labelled neocortical interneurons in clusters with high possibility of clonal relation preferentially form electrical, but not chemical, synapses...

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Autores principales: Xin-Jun Zhang, Zhizhong Li, Zhi Han, Khadeejah T. Sultan, Kun Huang, Song-Hai Shi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/040fe8c8a97a4be78af7057bb526c6ea
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Sumario:Developmental neuroscientists have long asked if clonally-related neurons retain functional relationships after maturation. The authors show that sparsely labelled neocortical interneurons in clusters with high possibility of clonal relation preferentially form electrical, but not chemical, synapses.