Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets

Epigenetic and transcriptional dynamics are critical for both tissue homeostasis and injury response in the kidney. Leveraging a single cell multiomics atlas of the developing mouse kidney, the authors reveal key events in chromatin regulation and gene expression dynamics during postnatal developmen...

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Autores principales:	Zhen Miao, Michael S. Balzer, Ziyuan Ma, Hongbo Liu, Junnan Wu, Rojesh Shrestha, Tamas Aranyi, Amy Kwan, Ayano Kondo, Marco Pontoglio, Junhyong Kim, Mingyao Li, Klaus H. Kaestner, Katalin Susztak
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/041359208fd74d1f952a6f800451b64e
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spelling	oai:doaj.org-article:041359208fd74d1f952a6f800451b64e2021-12-02T14:25:17ZSingle cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets10.1038/s41467-021-22266-12041-1723https://doaj.org/article/041359208fd74d1f952a6f800451b64e2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22266-1https://doaj.org/toc/2041-1723Epigenetic and transcriptional dynamics are critical for both tissue homeostasis and injury response in the kidney. Leveraging a single cell multiomics atlas of the developing mouse kidney, the authors reveal key events in chromatin regulation and gene expression dynamics during postnatal development.Zhen MiaoMichael S. BalzerZiyuan MaHongbo LiuJunnan WuRojesh ShresthaTamas AranyiAmy KwanAyano KondoMarco PontoglioJunhyong KimMingyao LiKlaus H. KaestnerKatalin SusztakNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhen Miao Michael S. Balzer Ziyuan Ma Hongbo Liu Junnan Wu Rojesh Shrestha Tamas Aranyi Amy Kwan Ayano Kondo Marco Pontoglio Junhyong Kim Mingyao Li Klaus H. Kaestner Katalin Susztak Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets
description	Epigenetic and transcriptional dynamics are critical for both tissue homeostasis and injury response in the kidney. Leveraging a single cell multiomics atlas of the developing mouse kidney, the authors reveal key events in chromatin regulation and gene expression dynamics during postnatal development.
format	article
author	Zhen Miao Michael S. Balzer Ziyuan Ma Hongbo Liu Junnan Wu Rojesh Shrestha Tamas Aranyi Amy Kwan Ayano Kondo Marco Pontoglio Junhyong Kim Mingyao Li Klaus H. Kaestner Katalin Susztak
author_facet	Zhen Miao Michael S. Balzer Ziyuan Ma Hongbo Liu Junnan Wu Rojesh Shrestha Tamas Aranyi Amy Kwan Ayano Kondo Marco Pontoglio Junhyong Kim Mingyao Li Klaus H. Kaestner Katalin Susztak
author_sort	Zhen Miao
title	Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets
title_short	Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets
title_full	Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets
title_fullStr	Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets
title_full_unstemmed	Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets
title_sort	single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/041359208fd74d1f952a6f800451b64e
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Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets

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