Preclinical therapeutic potential of a nitrosylating agent in the treatment of ovarian cancer.

Preclinical therapeutic potential of a nitrosylating agent in the treatment of ovarian cancer.

This study examines the role of s-nitrosylation in the growth of ovarian cancer using cell culture based and in vivo approaches. Using the nitrosylating agent, S-nitrosoglutathione (GSNO), a physiological nitric oxide molecule, we show that GSNO treatment inhibited proliferation of chemoresponsive a...

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Autores principales: Shailendra Giri, Ramandeep Rattan, Mandar Deshpande, Jacie L Maguire, Zachary Johnson, Rondell P Graham, Viji Shridhar
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/04204642a0234a30a6fe94cde88ff8e4
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