The low affinity neurotrophin receptor CD271 regulates phenotype switching in melanoma

The aggressive nature of melanoma cells relies on their ability to switch from a high-proliferative/low-invasive to a low-proliferative/high-invasive state; however, the mechanisms governing this switch are unclear. Here, using in vivo models of human melanoma, the authors show that CD271 is a key r...

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Auteurs principaux: Gaetana Restivo, Johanna Diener, Phil F. Cheng, Gregor Kiowski, Mario Bonalli, Thomas Biedermann, Ernst Reichmann, Mitchell P. Levesque, Reinhard Dummer, Lukas Sommer
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/0428808b8a974654b2d8209ef74be646
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