Neuromyelitis Optica (NMO) in Children: A Rare Case Report

Background: Neuromyelitis optica (NMO) is a rare autoimmune disease that covers 20-30% of diseases related to autoimmune disorders and about 1% of demyelination diseases. NMO symptoms are vary between individuals, there are generally 2 main symptoms, transverse myelitis and optic neuritis. This arti...

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Autores principales: Dodik Tugasworo, Aditya Kurnianto, Retnaningsih Retnaningsih, Yovita Andhitara, Rahmi Ardhini, Tomy Nugroho, Jethro Budiman
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Lenguaje:EN
Publicado: Diponegoro University 2020
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Acceso en línea:https://doaj.org/article/042a92cb85794b80849d03995a65c5f3
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spelling oai:doaj.org-article:042a92cb85794b80849d03995a65c5f32021-11-05T16:47:43ZNeuromyelitis Optica (NMO) in Children: A Rare Case Report2503-217810.14710/jbtr.v6i3.8451https://doaj.org/article/042a92cb85794b80849d03995a65c5f32020-12-01T00:00:00Zhttps://ejournal2.undip.ac.id/index.php/jbtr/article/view/8451https://doaj.org/toc/2503-2178Background: Neuromyelitis optica (NMO) is a rare autoimmune disease that covers 20-30% of diseases related to autoimmune disorders and about 1% of demyelination diseases. NMO symptoms are vary between individuals, there are generally 2 main symptoms, transverse myelitis and optic neuritis. This article reported a child with NMO disease based on The Consensus of the International Panel for NMO Diagnosis (IPND) 2015. Case Presentation: An 8-year old boy with spastic tetraparesis, bilateral nervus opticus dysfunction, urinary retention, and allodynia et causa suspected NMO. Patient received therapy using high-dose intravenous methylprednisolone and showing a clinical improvement. Conclusion: This patient was diagnosed NMO based on IPND 2015 with an unknown AQP4-Ab status accompanied by supporting clinical symptoms. The management of NMO with high-dose intravenous methylprednisolone in this patient provides a meaningful response to the clinical improvement of the disease.Dodik TugasworoAditya KurniantoRetnaningsih RetnaningsihYovita AndhitaraRahmi ArdhiniTomy NugrohoJethro BudimanDiponegoro Universityarticleneuromyelitis opticaautoimmunemethylprednisoloneMedicine (General)R5-920ENJournal of Biomedicine and Translational Research, Vol 6, Iss 3, Pp 92-96 (2020)
institution DOAJ
collection DOAJ
language EN
topic neuromyelitis optica
autoimmune
methylprednisolone
Medicine (General)
R5-920
spellingShingle neuromyelitis optica
autoimmune
methylprednisolone
Medicine (General)
R5-920
Dodik Tugasworo
Aditya Kurnianto
Retnaningsih Retnaningsih
Yovita Andhitara
Rahmi Ardhini
Tomy Nugroho
Jethro Budiman
Neuromyelitis Optica (NMO) in Children: A Rare Case Report
description Background: Neuromyelitis optica (NMO) is a rare autoimmune disease that covers 20-30% of diseases related to autoimmune disorders and about 1% of demyelination diseases. NMO symptoms are vary between individuals, there are generally 2 main symptoms, transverse myelitis and optic neuritis. This article reported a child with NMO disease based on The Consensus of the International Panel for NMO Diagnosis (IPND) 2015. Case Presentation: An 8-year old boy with spastic tetraparesis, bilateral nervus opticus dysfunction, urinary retention, and allodynia et causa suspected NMO. Patient received therapy using high-dose intravenous methylprednisolone and showing a clinical improvement. Conclusion: This patient was diagnosed NMO based on IPND 2015 with an unknown AQP4-Ab status accompanied by supporting clinical symptoms. The management of NMO with high-dose intravenous methylprednisolone in this patient provides a meaningful response to the clinical improvement of the disease.
format article
author Dodik Tugasworo
Aditya Kurnianto
Retnaningsih Retnaningsih
Yovita Andhitara
Rahmi Ardhini
Tomy Nugroho
Jethro Budiman
author_facet Dodik Tugasworo
Aditya Kurnianto
Retnaningsih Retnaningsih
Yovita Andhitara
Rahmi Ardhini
Tomy Nugroho
Jethro Budiman
author_sort Dodik Tugasworo
title Neuromyelitis Optica (NMO) in Children: A Rare Case Report
title_short Neuromyelitis Optica (NMO) in Children: A Rare Case Report
title_full Neuromyelitis Optica (NMO) in Children: A Rare Case Report
title_fullStr Neuromyelitis Optica (NMO) in Children: A Rare Case Report
title_full_unstemmed Neuromyelitis Optica (NMO) in Children: A Rare Case Report
title_sort neuromyelitis optica (nmo) in children: a rare case report
publisher Diponegoro University
publishDate 2020
url https://doaj.org/article/042a92cb85794b80849d03995a65c5f3
work_keys_str_mv AT dodiktugasworo neuromyelitisopticanmoinchildrenararecasereport
AT adityakurnianto neuromyelitisopticanmoinchildrenararecasereport
AT retnaningsihretnaningsih neuromyelitisopticanmoinchildrenararecasereport
AT yovitaandhitara neuromyelitisopticanmoinchildrenararecasereport
AT rahmiardhini neuromyelitisopticanmoinchildrenararecasereport
AT tomynugroho neuromyelitisopticanmoinchildrenararecasereport
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