A lipid gating mechanism for the channel-forming O antigen ABC transporter

Bacterial O antigen polysaccharides play a role in innate immune response evasion. Here, the authors uncover the ATP-bound structure of the Aquifex aeolicus WzmWzt O antigen ABC transporter, shedding light onto the mechanism of lipid-linked polysaccharide translocation.

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Autores principales:	Christopher A. Caffalette, Robin A. Corey, Mark S. P. Sansom, Phillip J. Stansfeld, Jochen Zimmer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/04315f1fe7d44079a2ae66d71dfc30db
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spelling	oai:doaj.org-article:04315f1fe7d44079a2ae66d71dfc30db2021-12-02T14:38:37ZA lipid gating mechanism for the channel-forming O antigen ABC transporter10.1038/s41467-019-08646-82041-1723https://doaj.org/article/04315f1fe7d44079a2ae66d71dfc30db2019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08646-8https://doaj.org/toc/2041-1723Bacterial O antigen polysaccharides play a role in innate immune response evasion. Here, the authors uncover the ATP-bound structure of the Aquifex aeolicus WzmWzt O antigen ABC transporter, shedding light onto the mechanism of lipid-linked polysaccharide translocation.Christopher A. CaffaletteRobin A. CoreyMark S. P. SansomPhillip J. StansfeldJochen ZimmerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Christopher A. Caffalette Robin A. Corey Mark S. P. Sansom Phillip J. Stansfeld Jochen Zimmer A lipid gating mechanism for the channel-forming O antigen ABC transporter
description	Bacterial O antigen polysaccharides play a role in innate immune response evasion. Here, the authors uncover the ATP-bound structure of the Aquifex aeolicus WzmWzt O antigen ABC transporter, shedding light onto the mechanism of lipid-linked polysaccharide translocation.
format	article
author	Christopher A. Caffalette Robin A. Corey Mark S. P. Sansom Phillip J. Stansfeld Jochen Zimmer
author_facet	Christopher A. Caffalette Robin A. Corey Mark S. P. Sansom Phillip J. Stansfeld Jochen Zimmer
author_sort	Christopher A. Caffalette
title	A lipid gating mechanism for the channel-forming O antigen ABC transporter
title_short	A lipid gating mechanism for the channel-forming O antigen ABC transporter
title_full	A lipid gating mechanism for the channel-forming O antigen ABC transporter
title_fullStr	A lipid gating mechanism for the channel-forming O antigen ABC transporter
title_full_unstemmed	A lipid gating mechanism for the channel-forming O antigen ABC transporter
title_sort	lipid gating mechanism for the channel-forming o antigen abc transporter
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/04315f1fe7d44079a2ae66d71dfc30db
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A lipid gating mechanism for the channel-forming O antigen ABC transporter

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