Integrated catalysis opens new arylation pathways via regiodivergent enzymatic C–H activation

Biocatalysis and metal catalysis often provide complimentary reactivities and selectivities. Here, the authors exploit the regioselectivity of an enzymatic C–H activation followed by palladium catalysed carbon-carbon bond formation in one pot, with membrane compartmentalization used to isolate the t...

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Auteurs principaux:	Jonathan Latham, Jean-Marc Henry, Humera H. Sharif, Binuraj R. K. Menon, Sarah A. Shepherd, Michael F. Greaney, Jason Micklefield
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2016
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/0433d1f6927342b4876e95b9f595c6da
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id	oai:doaj.org-article:0433d1f6927342b4876e95b9f595c6da
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spelling	oai:doaj.org-article:0433d1f6927342b4876e95b9f595c6da2021-12-02T15:35:23ZIntegrated catalysis opens new arylation pathways via regiodivergent enzymatic C–H activation10.1038/ncomms118732041-1723https://doaj.org/article/0433d1f6927342b4876e95b9f595c6da2016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11873https://doaj.org/toc/2041-1723Biocatalysis and metal catalysis often provide complimentary reactivities and selectivities. Here, the authors exploit the regioselectivity of an enzymatic C–H activation followed by palladium catalysed carbon-carbon bond formation in one pot, with membrane compartmentalization used to isolate the two chemistries.Jonathan LathamJean-Marc HenryHumera H. SharifBinuraj R. K. MenonSarah A. ShepherdMichael F. GreaneyJason MicklefieldNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jonathan Latham Jean-Marc Henry Humera H. Sharif Binuraj R. K. Menon Sarah A. Shepherd Michael F. Greaney Jason Micklefield Integrated catalysis opens new arylation pathways via regiodivergent enzymatic C–H activation
description	Biocatalysis and metal catalysis often provide complimentary reactivities and selectivities. Here, the authors exploit the regioselectivity of an enzymatic C–H activation followed by palladium catalysed carbon-carbon bond formation in one pot, with membrane compartmentalization used to isolate the two chemistries.
format	article
author	Jonathan Latham Jean-Marc Henry Humera H. Sharif Binuraj R. K. Menon Sarah A. Shepherd Michael F. Greaney Jason Micklefield
author_facet	Jonathan Latham Jean-Marc Henry Humera H. Sharif Binuraj R. K. Menon Sarah A. Shepherd Michael F. Greaney Jason Micklefield
author_sort	Jonathan Latham
title	Integrated catalysis opens new arylation pathways via regiodivergent enzymatic C–H activation
title_short	Integrated catalysis opens new arylation pathways via regiodivergent enzymatic C–H activation
title_full	Integrated catalysis opens new arylation pathways via regiodivergent enzymatic C–H activation
title_fullStr	Integrated catalysis opens new arylation pathways via regiodivergent enzymatic C–H activation
title_full_unstemmed	Integrated catalysis opens new arylation pathways via regiodivergent enzymatic C–H activation
title_sort	integrated catalysis opens new arylation pathways via regiodivergent enzymatic c–h activation
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/0433d1f6927342b4876e95b9f595c6da
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Integrated catalysis opens new arylation pathways via regiodivergent enzymatic C–H activation

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