A novel peptide derived from human apolipoprotein E is an inhibitor of tumor growth and ocular angiogenesis.

Angiogenesis is a hallmark of tumor development and metastasis and now a validated target for cancer treatment. We previously reported that a novel dimer peptide (apoEdp) derived from the receptor binding region of human apolipoprotein E (apoE) inhibits virus-induced angiogenesis. However, its role...

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Auteurs principaux: Partha S Bhattacharjee, Tashfin S Huq, Tarun K Mandal, Richard A Graves, Syed Muniruzzaman, Christian Clement, Harris E McFerrin, James M Hill
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
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R
Q
Accès en ligne:https://doaj.org/article/0435529784594d09a8ef39cc2d5295bc
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