Dynamic behaviour of human neuroepithelial cells in the developing forebrain

The dynamics of progenitor cells in human neocortex development has not been studied directly. Here, the authors timelapse image human neuroepithelial (NE) and radial glial (RG) cells in embryonic brain slices and find properties of NE cells and RG that are mimicked in cerebral organoids.

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Bibliographic Details
Main Authors: Lakshmi Subramanian, Marina Bershteyn, Mercedes F. Paredes, Arnold R. Kriegstein
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/04359e6e4d3e4bb591f9e41e9d3bfd03
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Summary:The dynamics of progenitor cells in human neocortex development has not been studied directly. Here, the authors timelapse image human neuroepithelial (NE) and radial glial (RG) cells in embryonic brain slices and find properties of NE cells and RG that are mimicked in cerebral organoids.