Antibody-powered nucleic acid release using a DNA-based nanomachine

Responsive molecular machines can perform specific tasks triggered by environmental or chemical stimuli. Here, the authors show that antibodies can be used as inputs to modulate the binding of a molecular cargo to a designed DNA-based nanomachine, with potential applications in diagnostics and drug...

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Autores principales:	Simona Ranallo, Carl Prévost-Tremblay, Andrea Idili, Alexis Vallée-Bélisle, Francesco Ricci
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0439f44ec2314b9ca5ff6fd6a0060036
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spelling	oai:doaj.org-article:0439f44ec2314b9ca5ff6fd6a00600362021-12-02T17:06:20ZAntibody-powered nucleic acid release using a DNA-based nanomachine10.1038/ncomms151502041-1723https://doaj.org/article/0439f44ec2314b9ca5ff6fd6a00600362017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15150https://doaj.org/toc/2041-1723Responsive molecular machines can perform specific tasks triggered by environmental or chemical stimuli. Here, the authors show that antibodies can be used as inputs to modulate the binding of a molecular cargo to a designed DNA-based nanomachine, with potential applications in diagnostics and drug delivery.Simona RanalloCarl Prévost-TremblayAndrea IdiliAlexis Vallée-BélisleFrancesco RicciNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Simona Ranallo Carl Prévost-Tremblay Andrea Idili Alexis Vallée-Bélisle Francesco Ricci Antibody-powered nucleic acid release using a DNA-based nanomachine
description	Responsive molecular machines can perform specific tasks triggered by environmental or chemical stimuli. Here, the authors show that antibodies can be used as inputs to modulate the binding of a molecular cargo to a designed DNA-based nanomachine, with potential applications in diagnostics and drug delivery.
format	article
author	Simona Ranallo Carl Prévost-Tremblay Andrea Idili Alexis Vallée-Bélisle Francesco Ricci
author_facet	Simona Ranallo Carl Prévost-Tremblay Andrea Idili Alexis Vallée-Bélisle Francesco Ricci
author_sort	Simona Ranallo
title	Antibody-powered nucleic acid release using a DNA-based nanomachine
title_short	Antibody-powered nucleic acid release using a DNA-based nanomachine
title_full	Antibody-powered nucleic acid release using a DNA-based nanomachine
title_fullStr	Antibody-powered nucleic acid release using a DNA-based nanomachine
title_full_unstemmed	Antibody-powered nucleic acid release using a DNA-based nanomachine
title_sort	antibody-powered nucleic acid release using a dna-based nanomachine
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/0439f44ec2314b9ca5ff6fd6a0060036
work_keys_str_mv	AT simonaranallo antibodypowerednucleicacidreleaseusingadnabasednanomachine AT carlprevosttremblay antibodypowerednucleicacidreleaseusingadnabasednanomachine AT andreaidili antibodypowerednucleicacidreleaseusingadnabasednanomachine AT alexisvalleebelisle antibodypowerednucleicacidreleaseusingadnabasednanomachine AT francescoricci antibodypowerednucleicacidreleaseusingadnabasednanomachine
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Antibody-powered nucleic acid release using a DNA-based nanomachine

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