Ubiquitous selection for mecA in community-associated MRSA across diverse chemical environments

The mecA gene confers resistance to many β-lactam antibiotics in community-associated MRSA bacteria. Here, Snitser et al. show that mecA also provides broad selective advantage across diverse chemical environments in the presence of subinhibitory β-lactam concentrations, by protecting the bacteria a...

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Autores principales:	Olga Snitser, Dor Russ, Laura K. Stone, Kathy K. Wang, Haleli Sharir, Noga Kozer, Galit Cohen, Haim M. Barr, Roy Kishony
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/04489c0e58f44ad5af07b868ae9d4e8d
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spelling	oai:doaj.org-article:04489c0e58f44ad5af07b868ae9d4e8d2021-12-02T15:33:52ZUbiquitous selection for mecA in community-associated MRSA across diverse chemical environments10.1038/s41467-020-19825-32041-1723https://doaj.org/article/04489c0e58f44ad5af07b868ae9d4e8d2020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19825-3https://doaj.org/toc/2041-1723The mecA gene confers resistance to many β-lactam antibiotics in community-associated MRSA bacteria. Here, Snitser et al. show that mecA also provides broad selective advantage across diverse chemical environments in the presence of subinhibitory β-lactam concentrations, by protecting the bacteria against increased cell-envelope permeability.Olga SnitserDor RussLaura K. StoneKathy K. WangHaleli SharirNoga KozerGalit CohenHaim M. BarrRoy KishonyNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Olga Snitser Dor Russ Laura K. Stone Kathy K. Wang Haleli Sharir Noga Kozer Galit Cohen Haim M. Barr Roy Kishony Ubiquitous selection for mecA in community-associated MRSA across diverse chemical environments
description	The mecA gene confers resistance to many β-lactam antibiotics in community-associated MRSA bacteria. Here, Snitser et al. show that mecA also provides broad selective advantage across diverse chemical environments in the presence of subinhibitory β-lactam concentrations, by protecting the bacteria against increased cell-envelope permeability.
format	article
author	Olga Snitser Dor Russ Laura K. Stone Kathy K. Wang Haleli Sharir Noga Kozer Galit Cohen Haim M. Barr Roy Kishony
author_facet	Olga Snitser Dor Russ Laura K. Stone Kathy K. Wang Haleli Sharir Noga Kozer Galit Cohen Haim M. Barr Roy Kishony
author_sort	Olga Snitser
title	Ubiquitous selection for mecA in community-associated MRSA across diverse chemical environments
title_short	Ubiquitous selection for mecA in community-associated MRSA across diverse chemical environments
title_full	Ubiquitous selection for mecA in community-associated MRSA across diverse chemical environments
title_fullStr	Ubiquitous selection for mecA in community-associated MRSA across diverse chemical environments
title_full_unstemmed	Ubiquitous selection for mecA in community-associated MRSA across diverse chemical environments
title_sort	ubiquitous selection for meca in community-associated mrsa across diverse chemical environments
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/04489c0e58f44ad5af07b868ae9d4e8d
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Ubiquitous selection for mecA in community-associated MRSA across diverse chemical environments

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