Exercise does not protect against MPTP-induced neurotoxicity in BDNF haploinsufficient mice.

Exercise does not protect against MPTP-induced neurotoxicity in BDNF haploinsufficient mice.

Exercise has been demonstrated to potently protect substantia nigra pars compacta (SN) dopaminergic neurons from 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity. One mechanism proposed to account for this neuroprotection is the upregulation of neurotrophic factors. Several...

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Autores principales: Kim M Gerecke, Yun Jiao, Viswajeeth Pagala, Richard J Smeyne
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/0449733c00204627974b8a39b8876ad2
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